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A single nucleotide polymorphism on chromosome 10 is highly predictive for the polled phenotype in Australian Merino sheep.

机译:10号染色体上的单核苷酸多态性可高度预测澳大利亚美利奴绵羊的轮询表型。

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摘要

The aim of this study was to fine map the genomic location of the Horns locus in the Australian Merino sheep population and to identify markers that can be used to predict the horn phenotype. A linkage disequilibrium analysis of horn data from Australian Merino sheep mapped the Horns locus to a small region on chromosome 10. A single nucleotide polymorphism in the region was found to be highly predictive for the polled phenotype in an experimental population of Merino sheep. This was owing to a dominance effect of one of the alleles when inherited maternally. It was suggested that a genetic test would provide a good predictor of the polled phenotype. Finally, an evaluation of industry data showed that the SNP is at very different frequencies in Poll Merino sheep that have been bred for polledness (based on phenotype alone) compared with the Merino sheep breed.Digital Object Identifier http://dx.doi.org/10.1111/j.1365-2052.2011.02271.x
机译:这项研究的目的是精细定位澳大利亚美利奴绵羊群体中 Horns 基因座的基因组位置,并确定可用于预测角表型的标记。对来自澳大利亚美利奴绵羊的牛角数据的连锁不平衡分析将 Horns 基因座映射到了10号染色体上的一个小区域。在该实验中,发现该区域的单核苷酸多态性可高度预测所轮询的表型美利奴绵羊的数量。这是由于母本遗传时等位基因之一具有优势作用。有人提出,基因检测可以很好地预测轮询表型。最后,对行业数据的评估表明,与美利奴绵羊品种相比,在为民意测验(仅基于表型)而繁殖的民意调查美利奴绵羊中,SNP的频率差异很大。数字对象标识符http://dx.doi。 org / 10.1111 / j.1365-2052.2011.02271.x

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