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Toxicological findings from 1587 civil aviation accident pilot fatalities, 1999-2003.

机译:1999-2003年1587次民航事故飞行员死亡的毒理学发现。

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INTRODUCTION: The prevalence of drug and ethanol use in aviation is monitored by the Federal Aviation Administration (FAA). Under such monitoring, toxicological studies for the 1989-1993 and 1994-1998 periods indicated lower percentages of the presence of controlled substances (illegal drugs) than that of prescription and nonprescription (over-the-counter) drugs in aviation accident pilot fatalities. In continuation, a toxicological assessment was made for an additional period of 5 yr. METHODS: Biosamples from aviation accident pilot fatalities submitted to the FAA Civil Aerospace Medical Institute (CAMI) are analyzed, and those findings are stored in a database. This database was examined for the 1999-2003 period for the presence of controlled substances (Schedules I-V), prescriptiononprescription drugs, and ethanol in the fatalities. RESULTS: Out of 1629 fatal aviation accidents from which CAMI received biosamples, pilots were fatally injured in 1587 accidents. Drugs and/or ethanol were found in 830 (52%) of the 1587 fatalities. Controlled substances from Schedules I-II (SI-II) and Schedules III-V (SIII-V) were detected in 113 and 42 pilots, respectively. Prescription drugs were present in 315 pilots, nonprescription drugs in 259, and ethanol in 101. SI-II substances were detected in 5 of 122 first-class medical certificate-holding airline transport pilots. In addition to the controlled substances, many of the prescriptiononprescription drugs found in the fatalities have the potential for impairing performance. CONCLUSIONS: Findings from this study were consistent with those of two previous toxicological studies and support the FAA's programs aimed at reducing the usage of performance-impairing substances.
机译:简介:航空中毒品和乙醇的使用受到联邦航空管理局(FAA)的监控。在这种监测下,对1989-1993年和1994-1998年期间的毒理学研究表明,在航空事故飞行员死亡人数中,受管制物质(非法药物)的存在百分比低于处方药和非处方(非处方药)药物的存在百分比。继续进行了为期5年的毒理学评估。方法:分析了提交给FAA民航医学研究所(CAMI)的航空事故飞行员死亡的生物样本,并将这些发现存储在数据库中。检查了该数据库的1999-2003年期间死亡人数中受控物质(附表I-V),处方药/非处方药和乙醇的存在。结果:在CAMI收到生物样本的1629例致命航空事故中,飞行员在1587事故中死亡。在1587人的死亡中,有830人(占52%)发现了毒品和/或乙醇。分别在113名和42名飞行员中检测到附表I-II(SI-II)和附表III-V(SIII-V)的受控物质。 315名飞行员中使用了处方药,259名飞行员中使用了非处方药,而101名飞行员中使用了乙醇。在122位持有医疗证书的头等舱航空运输飞行员中,有5名检测到了SI-II物质。除受管制物质外,在死亡中发现的许多处方药/非处方药也有可能损害性能。结论:这项研究的结果与先前的两项毒理学研究结果一致,并支持FAA旨在减少对性能有影响的物质的使用的计划。

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