The association of bone attrition with knee pain and other MRI features of osteoarthritis

摘要

Objective: To determine whether bone attrition (flattening or depression of the subchondral bone) was associated with the presence and seventy of knee pain and to evaluate the coexistence of attrition and other MRI features likely associated with pain. Methods: Participants in the Framingham Osteoarthritis Study, a community cohort unselected for OA, answered questions about knee pain and underwent knee x rays and MRI. Attrition, bone marrow lesions (BMLs) and effusions were scored on MRI using the WORMS scale. We assessed attrition in knees with and without pain, and using logistic regression examined its association with pain adjusting for age, gender, Kellgren-Lawrence (K-L) grade, BMI, BML and effusion. We also explored the relation between attrition, pain severity and nocturnal pain