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LETTER TO THE EDITOR Autologous stem cell transplantation for therapy-related acute myeloid leukemia and myelodysplastic syndrome

机译:致编辑的信自体干细胞移植治疗相关的急性髓性白血病和骨髓增生异常综合症

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摘要

N Kroger et al recently reported the results of a retrospective analysis of 65 patients undergoing autologous stem cell transplantation for therapy-related acute myeloid leukemia (t-AML) and myelodysplastic syndrome (t-MDS). The authors analyzed European bone marrow transplantation registry data and showed that the Kaplan-Meier estimates of the probability of 3-year overall and disease-free survival were 35 and 32%, respectively. These figures exceed the results obtained with allogeneic stem cell transplantation and support the autologous approach as an alternative for patients with t-AML/t-MDS.
机译:N Kroger等人最近报道了对65例接受自体干细胞移植治疗相关的急性髓性白血病(t-AML)和骨髓增生异常综合征(t-MDS)的患者进行回顾性分析的结果。作者分析了欧洲骨髓移植注册数据,发现Kaplan-Meier对3年总体生存率和无病生存率的估计分别为35%和32%。这些数字超过了同种异体干细胞移植获得的结果,并支持采用自体方法替代t-AML / t-MDS患者。

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