首页> 外文期刊>Annals of epidemiology >Racial differences in prostate cancer screening by family history.
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Racial differences in prostate cancer screening by family history.

机译:通过家族史筛查前列腺癌的种族差异。

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摘要

PURPOSE: Prostate cancer (CaP) is disproportionately prevalent among black, compared to white, men. Additionally, men with a family history of CaP have 75% to 80% higher risk of CaP. Therefore we examined racial variation in the association of family history of CaP and self-reported prostate-specific antigen (PSA) testing in the nationally-representative National Health Interview Survey (NHIS). METHODS: Data were obtained from the 2005 NHIS, including the Cancer Control Module supplement. We restricted the study sample to men over the age of 40 who reported having "ever heard of a PSA test" (N = 1,744). Men were considered to have a positive family history if either their biological father or at least one biological brother had been diagnosed with CaP. SUDAAN 9.0 was used to perform descriptive and multivariable logistic regression analyses. RESULTS: Men with a family history of CaP were more likely to have a PSA test than those who never had a PSA test (odds ratio [OR] = 1.8; 95% confidence interval [CI]: 1.3-2.5). Among blacks, men with a family history were not significantly more likely to have a PSA test. CONCLUSIONS: Despite having the highest risk of cancer, black men with a family history are not screened more than black men without a family history.
机译:目的:前列腺癌(CaP)在黑人男性中的比例不成比例。此外,有CaP家族史的男性发生CaP的风险高75%至80%。因此,我们在全国代表性的国家健康访问调查(NHIS)中检查了CaP家族史与自我报告的前列腺特异性抗原(PSA)检测之间的种族差异。方法:数据来自2005 NHIS,包括《癌症控制模块》增刊。我们将研究样本限制为40岁以上的男性,他们报告“从未听说过PSA测试”(N = 1,744)。如果他们的亲生父亲或至少一个亲生兄弟被诊断出患有CaP,则认为男性有阳性家族史。 SUDAAN 9.0用于执行描述性和多变量logistic回归分析。结果:具有CaP家族史的男性比从未接受过PSA检验的男性更有可能接受PSA检验(优势比[OR] = 1.8; 95%置信区间[CI]:1.3-2.5)。在黑人中,有家族病史的男性接受PSA测试的可能性不大。结论:尽管罹患癌症的风险最高,但具有家族病史的黑人的筛查没有没有家族病史的黑人更多。

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