eQTLs in platelets and iPSC-megakaryocytes

Middleton Elizabeth A.; Rowley Jesse W.

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eQTLs in platelets and iPSC-megakaryocytes

机译：血小板和IPSC-Megakaryocytes的eqtls

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摘要

In this issue of Blood, the study by Kammers et al(1) identifies genetic variants associated with gene expression in 290 platelet and 185 induced pluripotent stem cell (iPSC) megakaryocyte (MK) samples to fill in missing links between genotype and platelet phenotypes.

机译：在本期《血液》中，Kammers等人（1）的研究确定了290个血小板和185个诱导多能干细胞（iPSC）巨核细胞（MK）样本中与基因表达相关的遗传变异，以填补基因型和血小板表型之间的缺失联系。

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《Blood: The Journal of the American Society of Hematology》 |2021年第7期|共2页
作者
Middleton Elizabeth A.; Rowley Jesse W.;
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作者单位

Univ Utah Salt Lake City UT 84112 USA;

Univ Utah Salt Lake City UT 84112 USA;

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原文格式 PDF
正文语种 eng
中图分类血液及淋巴系疾病;
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1. Distant eQTLs and Non-coding Sequences Play Critical Roles in Regulating Gene Expression and Quantitative Trait Variation in Maize [J] . Haijun Liu, Qinghua Zhang, Jianbing Yan, 分子植物（英文版） . 2017,第003期
2. Flor Revisited (Again)：eQTL and Mutational Analysis of NB-LRR Mediated Immunity to Powdery Mildew in Barley [J] . Roger Wise, Priyanka Surana, Greg Fuerst, 农业科学学报（英文版） . 2014,第002期
3. Flor Revisited （Again） eQTL and Mutational Analysis of NB-LRR Mediated Immunity to Powdery Mildew in Barley [J] . Roger Wise, Priyanka Surana, Greg Fuerst, 农业科学学报：英文版 . 2014,第002期
4. Integration Analysis of m 6A-SNPs and eQTLs Associated With Sepsis Reveals Platelet Degranulation and Staphylococcus aureus Infection are Mediated by m 6A mRNA Methylation [J] . Xuri Sun, Yishuang Dai, Guoliang Tan, Frontiers in Genetics . 2020,第1期

机译：与败血症相关的M 6 a-snps和eqtls的整合分析显示血小板脱粒，并且<斜体>金黄色葡萄球菌感染由m 6 mRNA甲基化介导
5. Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2 [J] . Simon Lukas M., Chen Edward S., Edelstein Leonard C., The American Journal of Human Genetics . 2016,第5期

机译：人血小板eQTL的多组学综合分析揭示了丝裂霉素2中的替代起始位点
6. Genetic variations (eQTLs) in muscle transcriptome and mitochondrial genes, and trans-eQTL molecular pathways in feed efficiency from Danish breeding pigs [J] . Victor A. O. Carmelo, Haja N. Kadarmideen PLoS One . 2020,第9期

机译：肌肉转录组和线粒体基因中的遗传变异（EQTLS），以及来自丹麦繁殖猪的饲料效率的Trans-EQTL分子途径
7. eQTL epistasis: Detecting complex interaction effects between multiple loci from eQTL data [C] . Kang M., Li S., Liu C., IEEE International Conference on Bioinformatics and Biomedicine . 2013

机译：eQTL上位性：根据eQTL数据检测多个基因座之间的复杂相互作用
8. In Vitro Platelet Production: Promoting Megakaryocyte Terminal Differentiation, Demonstrating Platelet Functionality, and Developing an Automated Process for Platelet Harvest. [D] . Schlinker, Alaina C. 2014

机译：体外血小板生产：促进巨核细胞末端分化，展示血小板功能并开发血小板收获的自动化过程。
9. Integration Analysis of m6A-SNPs and eQTLs Associated With Sepsis Reveals Platelet Degranulation and Staphylococcus aureus Infection are Mediated by m6A mRNA Methylation [O] . Xuri Sun, Yishuang Dai, Guoliang Tan, 2020

机译：m6A-SNP和败血症相关的eQTL的整合分析显示血小板分离和金黄色葡萄球菌感染是由m6A mRNA甲基化介导的
10. Integration Analysis of m6A-SNPs and eQTLs Associated With Sepsis Reveals Platelet Degranulation and Staphylococcus aureus Infection are Mediated by m6A mRNA Methylation [O] . Xuri Sun, Yishuang Dai, Guoliang Tan, 2020

机译：与败血症相关的M6A-SNP和EQTL的整合分析显示血小板脱粒，金黄色葡萄球菌感染由M6A mRNA甲基化介导
11. Use of eQTL Analysis for the Discovery of Target Genes Identified by GWAS [R] . Thibodeau, S 2014

机译：使用eQTL分析发现GWas识别的目标基因

eQTLs in platelets and iPSC-megakaryocytes

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