首页> 外国专利> METHOD FOR MANUFACTURING PURIFIED BLOOD PLATELETS, METHOD FOR MANUFACTURING BLOOD PLATELET PREPARATION, METHOD FOR MANUFACTURING BLOOD PREPARATION, BLOOD PLATELET PRESERVATION FLUID, BLOOD PLATELET PRESERVATION AGENT, AND METHOD FOR PRESERVING BLOOD PLATELETS

METHOD FOR MANUFACTURING PURIFIED BLOOD PLATELETS, METHOD FOR MANUFACTURING BLOOD PLATELET PREPARATION, METHOD FOR MANUFACTURING BLOOD PREPARATION, BLOOD PLATELET PRESERVATION FLUID, BLOOD PLATELET PRESERVATION AGENT, AND METHOD FOR PRESERVING BLOOD PLATELETS

机译:制造纯化的血小板的方法,制造血液的血小板的制备方法,制造血液的方法,血液的血小板保存液,血液的血小板保存剂以及血液的保存方法

摘要

Provided is a method for manufacturing blood platelets that involves less damage to the blood platelets than a method in which the blood platelets are separated from a megakaryocyte culture with a filter and thereafter are concentrated using a hollow fiber membrane and washed using a hollow fiber membrane, and that can be executed in a shorter time than it takes to execute the abovementioned method so that damage to the blood platelets would be reduced. This method for manufacturing purified blood platelets is characterized by including a concentration step in which a megakaryocyte culture is concentrated and a centrifugal separation step in which the blood platelets are centrifugally separated from the obtained concentrate.
机译:本发明提供了一种血小板的制造方法,该方法与使用过滤器从巨核细胞培养物中分离血小板,然后使用中空丝膜浓缩,使用中空丝膜洗涤的方法相比,对血小板的损伤少。并且可以比执行上述方法所需的时间更短地执行,从而可以减少对血小板的损害。该纯化血小板的制造方法的特征在于包括浓缩步骤,其中浓缩巨核细胞培养物;以及离心分离步骤,其中将血小板从所得浓缩物中离心分离。

著录项

  • 公开/公告号WO2019059235A1

    专利类型

  • 公开/公告日2019-03-28

    原文格式PDF

  • 申请/专利权人 MEGAKARYON CORPORATION;

    申请/专利号WO2018JP34667

  • 发明设计人 TAKAHARA HIROYA;TOMIZUKA JUNKO;

    申请日2018-09-19

  • 分类号A61K35/19;A61P7/04;C12N5/078;C12N5/10;

  • 国家 WO

  • 入库时间 2022-08-21 11:55:40

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