Duration of bronchoprotection of inhaled ipratropium against inhaled methacholine.

摘要

Elevations of serum IgE and drag hypersensitivities have been commonly reported in patients with human immunodeficiency virus (HIV).1"6 Asthma, however, was rarely reported to occur in HIV-infected persons in the pre-antiretroviral therapy (ART) era.7 In the era of ART and immune reconstitution in HIV-infected individuals, there have been reports of increased incidence of asthma in patients with HIV.8 We report an overall increase in the incidence of asthma in our children infected with HIV and a correlation of asthma diagnosis with reconstitution of CD4+ T cells after ART therapy in HIV-infected children. These findings are of interest to HIV practitioners who will be treating patients with increased asthma symptoms and who will be concerned about the competence of newly reconstituted T cells. The findings are of interest to allergists because of the implication that CD4+ T cells are necessary for the localized inflammatory response in asthma.