Letter to the editor: Characterizing preclinieal model of ischemic heart failure: difference between LAD and LCx infarctions

摘要

to the editor: We read with great interest the recently published article of Ishikawa and colleagues (1). The authors established heart failure (HF) models via left anterior descending coronary artery (LAD) and left circumflex artery (LCx) occlusion. We would like to address several issues that we believe will better the understanding of the importance of study carried out. The authors did not specify whether they used a 6/12-lead ECG monitoring to detect ST-segment elevation myocardial infarction (STEMI). In contemporary practice, the clinical outcomes with LCx territory occlusion depend on if they have STEMI or non-STEMI. Only 30-50% of acute infarctions with occlusion of LCx present with STEMI. It is well documented that non-STEMI patients have better outcomes and are half as likely to develop HF as patients with STEMI (4).