The Association Between Empirical Antibiotic Treatment and Mortality in Severe Infections Caused by Carbapenem-resistant Gram-negative Bacteria: A Prospective Study

Pfeffer Iris; Paul Mical; Benattar Yael Dishon; Dickstein Yaakov; Bitterman Roni; Zayyad Hiba; Koppel Fidi; Zak-Doron Yael; Altunin Sergey; Andria Nizar; Neuberger Ami; Stern Anat; Petersiel Neta; Raines Marina; Karban Amir; Leibovici Leonard; Yahav Dafna; Eliakim-Raz Noa; Zusman Oren; Elbaz Michal; Atamna Heyam; Daitch Vered; Babich Tanya; Carmeli Yehuda; Nutman Amir; Adler Amos; Levi Inbar; Daikos George L.; Skiada Anna; Pavleas Ioannis; Antoniadou Anastasia; Kotsaki Antigoni; Durante-Mangoni Emanuele; Andini Roberto; Iossa Domenico; Bernardo Mariano; Cavezza Giusi; Bertolino Lorenzo; Giuffre Giuseppe; Giurazza Roberto; Cuccurullo Susanna; Galdo Maria; Murino Patrizia; Cristinziano Adriano; Corcione Antonio; Zampino Rosa; Pafundi Pia Clara; Mouton Johan; Friberg Lena; Kristoffersson Anders; Theuretzbacher Ursula

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The Association Between Empirical Antibiotic Treatment and Mortality in Severe Infections Caused by Carbapenem-resistant Gram-negative Bacteria: A Prospective Study

机译：耐肠道抗革兰阴性细菌造成的严重感染的经验抗生素治疗与死亡率之间的关联：一项前瞻性研究

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Background. Empirical colistin should be avoided. We aimed to evaluate the association between covering empirical antibiotics (EAT) and mortality for infections caused by carbapenem-resistant gram-negative bacteria (CRGNB).

机译：背景。应避免经验凉爽的山药。我们旨在评估覆盖经验抗生素（EAT）和死亡率的耐感染性与由CarbapeNem抗性革兰氏阴性细菌（CRGNB）引起的感染之间的关联。

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《Clinical infectious diseases》 |2018年第12期|共9页
作者
Pfeffer Iris; Paul Mical; Benattar Yael Dishon; Dickstein Yaakov; Bitterman Roni; Zayyad Hiba; Koppel Fidi; Zak-Doron Yael; Altunin Sergey; Andria Nizar; Neuberger Ami; Stern Anat; Petersiel Neta; Raines Marina; Karban Amir; Leibovici Leonard; Yahav Dafna; Eliakim-Raz Noa; Zusman Oren; Elbaz Michal; Atamna Heyam; Daitch Vered; Babich Tanya; Carmeli Yehuda; Nutman Amir; Adler Amos; Levi Inbar; Daikos George L.; Skiada Anna; Pavleas Ioannis; Antoniadou Anastasia; Kotsaki Antigoni; Durante-Mangoni Emanuele; Andini Roberto; Iossa Domenico; Bernardo Mariano; Cavezza Giusi; Bertolino Lorenzo; Giuffre Giuseppe; Giurazza Roberto; Cuccurullo Susanna; Galdo Maria; Murino Patrizia; Cristinziano Adriano; Corcione Antonio; Zampino Rosa; Pafundi Pia Clara; Mouton Johan; Friberg Lena; Kristoffersson Anders; Theuretzbacher Ursula;
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作者单位

Tel Aviv Univ Tel Aviv Sourasky Med Ctr Div Epidemiol &

Prevent Med Ramat Aviv Israel;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
appropriate empirical antibiotics; multidrug-resistant bacteria; carbapenemase-producing; colistin; gram-negative bacteria;

机译：适当的经验抗生素;多药物抗菌;生产碳酸酶;胚胎;革兰氏阴性细菌;

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1. The Association Between Empirical Antibiotic Treatment and Mortality in Severe Infections Caused by Carbapenem-resistant Gram-negative Bacteria: A Prospective Study [J] . Pfeffer Iris, Paul Mical, Benattar Yael Dishon, Clinical infectious diseases . 2018,第12期

机译：耐肠道抗革兰阴性细菌造成的严重感染的经验抗生素治疗与死亡率之间的关联：一项前瞻性研究
2. Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections (AIDA): a study protocol [J] . Amir Nutman, Amos Adler, Anastasia Antoniadou, BMJ Open . 2016,第4期

机译：一项多中心开放标签的随机对照试验，比较单独的粘菌素和粘菌素加美罗培南在治疗对碳青霉烯耐药的革兰氏阴性菌感染（AIDA）引起的严重感染中的作用：一项研究方案
3. Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections (AIDA): a study protocol [J] . Amir Nutman, Amos Adler, Anastasia Antoniadou, BMJ Open . 2016,第4期

机译：一项多中心开放标签的随机对照试验，比较单独的粘菌素和粘菌素加美罗培南在治疗对碳青霉烯耐药的革兰氏阴性菌感染（AIDA）引起的严重感染中的作用：一项研究方案
4. Efficacy and Safety of Polymyxin B in the Treatment of Infections Caused by Multidrug- Resistant Gram-Negative Infections: A Retrospective Review [C] . Oh HML, Gan LH, Wee I International Congress of Chemotherapy and Infection . 2009

机译：多种抗革兰阴性感染治疗感染治疗感染的疗效和安全性：回顾性综述
5. Immunotherapy Improves Outcomes by Ameliorating Inflammation during Infections Caused by Gram-Negative Bacteria [D] . Nielsen, Travis Brady. 2018

机译：免疫疗法通过改善由革兰阴性细菌引起的感染炎症改善炎症的结果
6. Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections (AIDA): a study protocol [O] . Yaakov Dickstein, Leonard Leibovici, Dafna Yahav, 2016

机译：多中心开放标签随机对照试验比较单独的粘菌素与粘菌素加美罗培南在治疗对碳青霉烯耐药的革兰氏阴性菌感染（AIDA）引起的严重感染中的作用：一项研究方案
7. Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections (AIDA) : a study protocol [O] . Dickstein, Yaakov, Leibovici, Leonard, Yahav, Dafna, 2016

机译：一项多中心开放标签随机对照试验，比较单独的粘菌素和粘菌素加美罗培南在治疗对碳青霉烯耐药的革兰氏阴性菌感染（AIDA）引起的严重感染中的作用：一项研究方案

The Association Between Empirical Antibiotic Treatment and Mortality in Severe Infections Caused by Carbapenem-resistant Gram-negative Bacteria: A Prospective Study

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