Omalizumab therapy for refractory allergic fungal rhinosinusitis patients with moderate or severe asthma

摘要

Purpose: 1. To assess the efficacy of omalizumab therapy in improving sinonasal outcomes in refractory allergic fungal rhinosinusitis (AFRS) patients with moderate or severe asthma. 2. To determine if omalizumab therapy reduces the usage of corticosteroids or antifungal therapy in AFRS patients