A3 ADENOSINE RECEPTOR (A3AR) AGONIST, AST-004, IS NEUROPROTECTIVE IN BLUNT AND BLAST MODELS OF TRAUMATIC BRAIN INJURY (TBI)

Bozdemir Eda; Vigil Fabio A.; Bugay Vladislav; Espinoza Liliana; Chun Sang H.; Holstein Deborah M.; Elliot Rowe; Sprague Cassie; Rule Gregory; Korinek William; Liston Theodore; Cavazos Jose E.; Shapiro Mark S.; Zamora David; Brenner Robert; Lechleiter James D.

首页> 外文期刊>Journal of neurotrauma >A3 ADENOSINE RECEPTOR (A3AR) AGONIST, AST-004, IS NEUROPROTECTIVE IN BLUNT AND BLAST MODELS OF TRAUMATIC BRAIN INJURY (TBI)

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A3 ADENOSINE RECEPTOR (A3AR) AGONIST, AST-004, IS NEUROPROTECTIVE IN BLUNT AND BLAST MODELS OF TRAUMATIC BRAIN INJURY (TBI)

机译：A3腺苷受体（A3AR）激动剂，AST-004，是创伤性脑损伤的钝和爆炸模型中的神经保护性（TBI）

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来源
《Journal of neurotrauma》 |2019年第13期|共1页
作者
Bozdemir Eda; Vigil Fabio A.; Bugay Vladislav; Espinoza Liliana; Chun Sang H.; Holstein Deborah M.; Elliot Rowe; Sprague Cassie; Rule Gregory; Korinek William; Liston Theodore; Cavazos Jose E.; Shapiro Mark S.; Zamora David; Brenner Robert; Lechleiter James D.;
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作者单位

Univ Texas Hlth Sci Ctr San Antonio San Antonio TX 78229 USA;

Univ Texas Hlth Sci Ctr San Antonio San Antonio TX 78229 USA;

Univ Texas Hlth Sci Ctr San Antonio San Antonio TX 78229 USA;

Univ Texas Hlth Sci Ctr San Antonio San Antonio TX 78229 USA;

Univ Texas Hlth Sci Ctr San Antonio San Antonio TX 78229 USA;

Univ Texas Hlth Sci Ctr San Antonio San Antonio TX 78229 USA;

US Army Inst Surg Res San Antonio TX USA;

US Army Inst Surg Res San Antonio TX USA;

Appl Res Associates San Antonio TX USA;

Astrocyte Pharmaceut Inc Cambridge MA USA;

Astrocyte Pharmaceut Inc Cambridge MA USA;

Univ Texas Hlth Sci Ctr San Antonio San Antonio TX 78229 USA;

Univ Texas Hlth Sci Ctr San Antonio San Antonio TX 78229 USA;

US Army Inst Surg Res San Antonio TX USA;

Univ Texas Hlth Sci Ctr San Antonio San Antonio TX 78229 USA;

Univ Texas Hlth Sci Ctr San Antonio San Antonio TX 78229 USA;

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原文格式 PDF
正文语种 eng
中图分类头部及神经外科学;
关键词
TBI; A3AR; Seizure; Cell death; BBB;

机译：TBI;A3AR;癫痫发作;细胞死亡;BBB;

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专利

1. A3 ADENOSINE RECEPTOR (A3AR) AGONIST, AST-004, IS NEUROPROTECTIVE IN BLUNT AND BLAST MODELS OF TRAUMATIC BRAIN INJURY (TBI) [J] . Bozdemir Eda, Vigil Fabio A., Bugay Vladislav, Journal of neurotrauma . 2019,第13期

机译：A3腺苷受体（A3AR）激动剂，AST-004，是创伤性脑损伤的钝和爆炸模型中的神经保护性（TBI）
2. 384 Phase 1/2 trial of CF102, a selective {A3} adenosine receptor (A3AR) agonist, in patients with hepatocellular carcinoma (HCC) [J] . S. Stemmer, M.H. Silverman, W.D. Kerns, European Journal of Cancer Supplements . 2010,第7期

机译：选择性 {A3 }腺苷受体（A3AR）激动剂CF102在肝细胞癌（HCC）患者中的384次1/2期试验
3. Targeting the A3 adenosine receptor for cancer therapy: inhibition of prostate carcinoma cell growth by A3AR agonist. [J] . Fishman P, Bar Yehuda S, Ardon E, Anticancer Research: International Journal of Cancer Research and Treatment . 2003,第3Appa期

机译：针对A3腺苷受体进行癌症治疗：通过A3AR激动剂抑制前列腺癌细胞的生长。
4. MRI-Based Three Dimensional Modeling of Blast Traumatic Brain Injury (bTBI) [C] . SHAILESH GANPULE, NAMAS CHANDRA, LINXIAGU ASME International Mechanical Engineering Congress and Exposition . 2012

机译：基于MRI的爆炸创伤性脑损伤三维建模（BTBI）
5. Mechanics of blast loading on post-mortem human and surrogate heads in the study of traumatic brain injury (TBI) using experimental and computational approaches. [D] . Ganpule, Shailesh Govind. 2013

机译：在使用实验和计算方法研究颅脑损伤（TBI）的尸体和尸体头部后，爆炸载荷的力学原理。
6. Pharmacological and Therapeutic Effects of A3 Adenosine Receptor (A3AR) Agonists [O] . Pnina Fishman, Sara Bar-Yehuda, Bruce T. Liang, -1

机译：A3腺苷受体（A3AR）激动剂的药理学和治疗效果
7. Neuroprotective Roles of the Adenosine A3 Receptor Agonist AST-004 in Mouse Model of Traumatic Brain Injury [O] . Eda Bozdemir, Fabio A Vigil, Sang H Chun, 2021

机译：腺苷A3受体激动剂AST-004在创伤性脑损伤小鼠模型中的神经保护作用
8. Minimizing Skeletal Muscle Injury to Ischemia/Reperfusion with Adenosine A3 Receptor Agonists: Role of Matrix Metalloproteases. [R] . Urso, M. L., Zambraski, E. J., Liang, B. T. 2009

机译：用腺苷a3受体激动剂减少骨骼肌损伤缺血/再灌注：基质金属蛋白酶的作用。

A3 ADENOSINE RECEPTOR (A3AR) AGONIST, AST-004, IS NEUROPROTECTIVE IN BLUNT AND BLAST MODELS OF TRAUMATIC BRAIN INJURY (TBI)

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