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Modern Management of Anthracycline-Induced Cardiotoxicity in Lymphoma Patients: Low Occurrence of Cardiotoxicity with Comprehensive Assessment and Tailored Substitution by Nonpegylated Liposomal Doxorubicin

机译:现代管理淋巴瘤患者的蒽曲素诱导的心脏毒性:非通过综合评估和量身定制替代的心脏毒性低发生的血管毒性

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摘要

Background. Anthracyclines (AC) are still undeniable drugs in lymphoma treatment, despite occasionally causing cardiotoxicity. Liposomal AC may reduce cardiotoxicity while retaining clinical efficacy; also, biomarker monitoring during chemotherapy allows early detection of cardiac damage, enabling strategies to prevent left ventricular ejection fraction (LVEF) deterioration.
机译:背景。 尽管偶尔导致心脏毒性,蒽环类(AC)仍然是不可否认的淋巴瘤治疗药物。 脂质体AC可以减少心脏毒性,同时保持临床疗效; 此外,化疗期间的生物标志物监测允许早期检测心脏损伤,使策略能够防止左心室喷射分数(LVEF)劣化。

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