Short communication: Factors influencing time to CD4+ T cell counts 200 cells/mm3 in HIV-infected individuals with CD4 + T Cell 50 Cells/mm3 at the time of starting combination antiretroviral therapy

摘要

We evaluated factors influencing time to CD4+ T cell counts 200 cells/mm3 in HIV-infected individuals with CD4+ T cell 50 cells/mm3 starting combination antiretroviral therapy (cART). We included a total of 29 patients on successful cART for more than 1 year. In a logistic regression model, higher pre-cART CD4+ T cell counts were significantly associated with shorter time to CD4+ T cell counts 200cells/mm3 in HIV-infected individuals with baseline CD4+ T cell 50 cells/mm3. In survival analysis, patients having higher pre-cART CD4+ T cell counts, especially 40-49 cells/mm3, were at significantly higher risk of achieving CD4 + T cell counts 200 cells/mm3.