Development of a Targeted NGS Panel for Solid Tumor Actionable Gene Targets using Multiplex PCR-based Enrichment in an Integrated Fluidic Circuit

Chen P.; Wang X.; Gong H.; Lespagnol A.; Meyers S.; Do D.; Gonzalez M.; McLean L.; Goralski T.; Hunt B.

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Development of a Targeted NGS Panel for Solid Tumor Actionable Gene Targets using Multiplex PCR-based Enrichment in an Integrated Fluidic Circuit

机译：在综合流体回路中使用多重PCR基富集的固体肿瘤可致动基因靶标的靶向NGS面板的研制

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来源
《The Journal of molecular diagnostics: JMD》 |2018年第6期|共1页
作者
Chen P.; Wang X.; Gong H.; Lespagnol A.; Meyers S.; Do D.; Gonzalez M.; McLean L.; Goralski T.; Hunt B.;
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作者单位

Fluidigm San Francisco CA USA;

Fluidigm San Francisco CA USA;

Fluidigm San Francisco CA USA;

CHU Rennes Rennes France;

Fluidigm San Francisco CA USA;

Fluidigm San Francisco CA USA;

Fluidigm San Francisco CA USA;

Fluidigm San Francisco CA USA;

Fluidigm San Francisco CA USA;

Fluidigm San Francisco CA USA;

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原文格式 PDF
正文语种 eng
中图分类临床医学;
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专利

1. Development of a Targeted NGS Panel for Solid Tumor Actionable Gene Targets using Multiplex PCR-based Enrichment in an Integrated Fluidic Circuit [J] . Chen P., Wang X., Gong H., The Journal of molecular diagnostics: JMD . 2018,第6期

机译：在综合流体回路中使用多重PCR基富集的固体肿瘤可致动基因靶标的靶向NGS面板的研制
2. Targeted capture-based NGS is superior to multiplex PCR-based NGS for hereditary BRCA1 and BRCA2 gene analysis in FFPE tumor samples [J] . Falk Zakrzewski, Laura Gieldon, Andreas Rump, BMC Cancer . 2019,第1期

机译：基于靶向捕获的NGS优于FFPE肿瘤样本中的遗传性BRCA1和BRCA2基因分析的基于多重PCR的NGS
3. Is Next-Generation Sequencing (NGS) Ready for Routine Clinical Practice in Advanced Well Differentiated Pancreatic Neuroendocrine Tumors (WD panNETs): Results of a Prospective Study Utilizing MSK-IMPACT (Memorial Sloan Kettering Integrated Mutation Profiling of Actionable Cancer Targets) [J] . Raj Nitya, Soumerai Tara, Valentino Emily, Pancreas . 2016,第3期

机译：下一代测序（NGS）是否已准备好用于晚期高度分化的胰腺神经内分泌肿瘤（WD panNETs）的常规临床实践：利用MSK-IMPACT（纪念斯隆·凯特琳（Meanial Sloan Kettering）综合突变分析可操作的癌症目标）的前瞻性研究结果
4. Quantitative Detection and Monitoring of Myeloid Cancers and HIV-Infections Using Picodroplet Single Molecule PCR-Based Targeted NGS and Digital PCR/RT-PCR [C] . Michael L. Samuels, Steve K. Kotsopoulos, Frances Long, International Molecular Medicine Tri-Conference. . 2016

机译：使用Picodroplet单分子PCR基靶向NGS和Digital PCR / RT-PCR的定量检测和监测骨髓癌和HIV感染
5. Engineering tumor-targeted poly(amidoamine) (PAMAM) dendrimers for improved penetration and cellular delivery of short-interfering RNA (siRNA) through solid tumors [D] . Waite, Carolyn Leigh 2011

机译：工程化靶向肿瘤的聚（酰胺基胺）（PAMAM）树状大分子，以提高短干扰RNA（siRNA）通过实体瘤的渗透和细胞递送
6. Targeted capture-based NGS is superior to multiplex PCR-based NGS for hereditary BRCA1 and BRCA2 gene analysis in FFPE tumor samples [O] . Falk Zakrzewski, Laura Gieldon, Andreas Rump, 2019

机译：针对FFPE肿瘤样本中的遗传性BRCA1和BRCA2基因分析靶向捕获的NGS优于基于多重PCR的NGS
7. A Multiplex PCR-Based Next Generation Sequencing-Panel to Identify Mutations for Targeted Therapy in Breast Cancer Circulating Tumor Cells [O] . André Franken, Mahdi Rivandi, Liwen Yang, 2020

机译：基于多重PCR的下一代测序面板，以鉴定乳腺癌循环肿瘤细胞靶向治疗的突变

Development of a Targeted NGS Panel for Solid Tumor Actionable Gene Targets using Multiplex PCR-based Enrichment in an Integrated Fluidic Circuit

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