Promoter methylation and clinical significance of GPX3 in esophageal squamous cell carcinoma

Lin Youbin; Zhang Ying; Chen Yelong; Liu Zhaoyong

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Promoter methylation and clinical significance of GPX3 in esophageal squamous cell carcinoma

机译：GPX3在食管鳞状细胞癌中的启动子甲基化及临床意义

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Background: Glutathione peroxidase 3 (GPX3) provides critical protection against reactive oxygen species (ROS) in cells. Downregulation of GPX3 may contribute to carcinogenesis of esophageal squamous cell carcinoma (ESCC), but the mechanisms are not clear.

机译：背景：谷胱甘肽过氧化物酶3（GPX3）在细胞中反对反应性氧物质（ROS）提供了关键保护。 GPX3的下调可能有助于食道鳞状细胞癌（ESCC）的致癌，但机制尚不清楚。

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来源
《Pathology Research and Practice》 |2019年第11期|共5页
作者
Lin Youbin; Zhang Ying; Chen Yelong; Liu Zhaoyong;
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作者单位

Shantou Univ Affiliated Hosp 1 Med Coll Dept Orthopaed 57 Changping Rd Shantou 515041;

Sun Yat Sen Univ Canc Ctr Dept Pathol 651 Dongfeng East Rd Guangzhou 510060 Guangdong Peoples;

Shantou Univ Affiliated Hosp 1 Med Coll Dept Orthopaed 57 Changping Rd Shantou 515041;

Shantou Univ Affiliated Hosp 1 Med Coll Dept Orthopaed 57 Changping Rd Shantou 515041;

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原文格式 PDF
正文语种 eng
中图分类病理学;
关键词
GPX3; ESCC; Prognosis; IHC; Survival;

机译：GPX3;ESCC;预后;IHC;生存;

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专利

1. Promoter methylation and clinical significance of GPX3 in esophageal squamous cell carcinoma [J] . Lin Youbin, Zhang Ying, Chen Yelong, Pathology Research and Practice . 2019,第11期

机译：GPX3在食管鳞状细胞癌中的启动子甲基化及临床意义
2. Clinical significance of methylation of E-cadherin and p14ARF gene promoters in skin squamous cell carcinoma tissues [J] . Jian Wu, Jin-Rong Zhang, Jie Qin International Journal of Clinical and Experimental Medicine . 2014,第7期

机译：皮肤鳞状细胞癌组织中E-cadherin和p14ARF基因启动子甲基化的临床意义
3. Quantitative detection of TIMP-3 promoter hypermethylation and its prognostic significance in esophageal squamous cell carcinoma. [J] . Ninomiya I, Kawakami K, Fushida S, Oncology reports . 2008,第6期

机译：TIMP-3启动子高甲基化的定量检测及其在食管鳞状细胞癌中的预后意义。
4. Clinical Significance of Cortactin and Cyclin D1 Expression in Squamous Cell Carcinomas of the Tongue [C] . Nakamori K., Dehari H., Imai T., European Association of Cranio-Maxillo-Facial Surgery . 2010

机译：舌鳞状细胞癌中皮质素和细胞周期蛋白D1表达的临床意义
5. MicroRNA-137 promoter methylation as an etiologic and prognostic biomarker for squamous cell carcinoma of the head and neck. [D] . Langevin, Scott M. 2010

机译：MicroRNA-137启动子甲基化作为头颈部鳞状细胞癌的病因和预后生物标志物。
6. Clinical significance of methylation of E-cadherin and p14ARF gene promoters in skin squamous cell carcinoma tissues [O] . Jian Wu, Jin-Rong Zhang, Jie Qin 2005

机译：皮肤鳞状细胞癌组织中E-钙黏着蛋白和p14ARF基因启动子甲基化的临床意义
7. The Association and Clinical Significance of CDKN2A Promoter Methylation in Head and Neck Squamous Cell Carcinoma: a Meta-Analysis [O] . Chongchang Zhou, Zhisen Shen, Dong Ye, 2018

机译：CDKN2A启动子甲基化在头颈鳞癌中的关联及临床意义：荟萃分析

Promoter methylation and clinical significance of GPX3 in esophageal squamous cell carcinoma

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