Doxorubicin Hydrochloride Loaded Zymosan-Polyethylenimine Biopolymeric Nanoparticles for Dual 'Chemoimmunotherapeutic' Intervention in Breast Cancer

Pawar Vivek K.; Singh Yuvraj; Sharma Komal; Shrivastav Arpita; Sharma Abhisheak; Singh Akhilesh; Meher Jaya Gopal; Singh Pankaj; Raval Kavit; Bora Himangshu K.; Datta Dipak; Lal Jawahar; Chourasia Manish K.

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Doxorubicin Hydrochloride Loaded Zymosan-Polyethylenimine Biopolymeric Nanoparticles for Dual 'Chemoimmunotherapeutic' Intervention in Breast Cancer

机译：盐酸多柔比星盐酸盐酵母 - 聚乙烯亚氨基生物聚合纳米粒子用于双重'化疗的乳腺癌干预

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Objective To utilize nanoparticles produced by condensation of zymosan (an immunotherapeutic polysaccharide) with pegylated polyethylenimine (PEG-PEI) for dual intervention in breast cancer by modulating tumor microenvironment and direct chemotherapy.

机译：目的利用通过调节肿瘤微环境和直接化疗的乳腺化聚乙烯亚胺（PEG-PEI）用聚乙酰化聚乙烯亚胺（PEG-PEI）缩合酵素化聚乙烯酸酯（PEG-PEI）来利用纳米粒子。

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来源
《Pharmaceutical research》 |2017年第9期|共15页
作者
Pawar Vivek K.; Singh Yuvraj; Sharma Komal; Shrivastav Arpita; Sharma Abhisheak; Singh Akhilesh; Meher Jaya Gopal; Singh Pankaj; Raval Kavit; Bora Himangshu K.; Datta Dipak; Lal Jawahar; Chourasia Manish K.;
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作者单位

CSIR Cent Drug Res Inst Div Pharmaceut Lucknow 226031 Uttar Pradesh India;

CSIR Cent Drug Res Inst Div Pharmaceut Lucknow 226031 Uttar Pradesh India;

CSIR Cent Drug Res Inst Div Pharmaceut Lucknow 226031 Uttar Pradesh India;

CSIR Cent Drug Res Inst Div Pharmaceut Lucknow 226031 Uttar Pradesh India;

Acad Sci &

Innovat Res New Delhi 110025 India;

CSIR Cent Drug Res Inst Div Biochem Lucknow 226031 Uttar Pradesh India;

CSIR Cent Drug Res Inst Div Pharmaceut Lucknow 226031 Uttar Pradesh India;

CSIR Cent Drug Res Inst Div Pharmaceut Lucknow 226031 Uttar Pradesh India;

CSIR Cent Drug Res Inst Div Pharmaceut Lucknow 226031 Uttar Pradesh India;

CSIR Cent Drug Res Inst Lab Anim Facil Lucknow 226031 Uttar Pradesh India;

CSIR Cent Drug Res Inst Div Biochem Lucknow 226031 Uttar Pradesh India;

CSIR Cent Drug Res Inst Pharmacokinet &

Metab Div Lucknow 226031 Uttar Pradesh India;

CSIR Cent Drug Res Inst Div Pharmaceut Lucknow 226031 Uttar Pradesh India;

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原文格式 PDF
正文语种 eng
中图分类生药学（天然药物学）;
关键词
angiogenesis; chemoimmunotherapeutic nanoparticles; cytokine; hypoxia; tumor associated macrophages;

机译：血管生成;化学用药纳米粒子;细胞因子;缺氧;肿瘤相关的巨噬细胞;

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1. Doxorubicin Hydrochloride Loaded Zymosan-Polyethylenimine Biopolymeric Nanoparticles for Dual 'Chemoimmunotherapeutic' Intervention in Breast Cancer [J] . Pawar Vivek K., Singh Yuvraj, Sharma Komal, Pharmaceutical research . 2017,第9期

机译：盐酸多柔比星盐酸盐酵母 - 聚乙烯亚氨基生物聚合纳米粒子用于双重'化疗的乳腺癌干预
2. Two-stage pH-sensitive doxorubicin hydrochloride loaded core–shell nanoparticles with dual drug-loading strategies for the potential anti-tumor treatment [J] . Xiaoyue Yu, Bo Zhang, Tianqi Wang, RSC Advances . 2016,第106期

机译：盐酸盐酸盐的两阶段pH敏感的多柔比星，具有双药物载体纳米粒子，具有潜在的抗肿瘤治疗的双重药物载荷策略
3. Doxorubicin Hydrochloride-Loaded Mesoporous Silica Nanoparticles Inhibit Non-Small Cell Lung Cancer Metastasis by Suppressing VEGF-Mediated Angiogenesis [J] . Zhang Min, Jiang Li Journal of biomedical nanotechnology . 2016,第11期

机译：盐酸阿霉素负载的介孔二氧化硅纳米颗粒通过抑制VEGF介导的血管生成抑制非小细胞肺癌转移。
4. Epirubicin hydrochloride loaded poly (butylcyanoacrylate) nanoparticles: Formulation optimization, characterization and in-vitro evaluation in human breast cancer cell lines [C] . Prudhviraju Dantuluri, Neha Shah, M. R. Sunil Kumar, Nanotechnology 2009 : Technical proceedings . 2009

机译：盐酸表柔比星负载的聚（氰基丙烯酸丁酯）纳米颗粒：在人类乳腺癌细胞系中的配方优化，表征和体外评估
5. Development of indocyanine green loaded long circulating and folate-receptor-targeted PLGA nanoparticles for photodynamic therapy of breast cancer. [D] . Tikekar, Shilpa. 2011

机译：吲哚菁绿负载长循环和叶酸受体靶向PLGA纳米粒子的开发，用于乳腺癌的光动力治疗。
6. Doxorubicin Hydrochloride-Loaded Nonionic SurfactantVesicles to Treat Metastatic and Non-Metastatic Breast Cancer [O] . Martina Di Francesco, □, Christian Celia, 2021

机译：盐酸多柔比星负载的非离子表面活性剂囊泡治疗转移性和非转移性乳腺癌
7. Doxorubicin Hydrochloride-Loaded Nonionic Surfactant Vesicles to Treat Metastatic and Non-Metastatic Breast Cancer [O] . Martina Di Francesco, Christian Celia, Maria Chiara Cristiano, 2021

机译：盐酸多柔比星负载的非离子表面活性剂囊泡治疗转移性和非转移性乳腺癌
8. Mechanism-Based Enhanced Delivery of Drug-Loaded Targeted Nanoparticles for Breast Cancer Therapy. [R] . Band, H., Bronich, T. 2014

机译：基于机制的药物负载靶向纳米粒子的增强递送用于乳腺癌治疗。

Doxorubicin Hydrochloride Loaded Zymosan-Polyethylenimine Biopolymeric Nanoparticles for Dual 'Chemoimmunotherapeutic' Intervention in Breast Cancer

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