首页> 外文期刊>Rapid Communications in Mass Spectrometry: RCM >Development of a method for the determination of 8‐iso‐PGF2α in sheep and goat plasma using solid‐phase microextraction and ultra‐performance liquid chromatography/tandem mass spectrometry

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Development of a method for the determination of 8‐iso‐PGF2α in sheep and goat plasma using solid‐phase microextraction and ultra‐performance liquid chromatography/tandem mass spectrometry

机译：使用固相微萃取和超高效液相色谱/串联质谱法测定绵羊和山羊血浆中8-ISO-PGF2α的方法的研制

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Rationale >Isoprostane 8‐iso‐PGF2α is a biomarker of lipid peroxidation in cell membranes. The method developed to measure plasma total levels (esterified + free) of 8‐iso‐PGF2α must be reproducible and be able to reduce the use of solvents in solid phase extraction. It should be useful to evaluate oxidative stress due to the excess of free radicals that are generated by some disorder or disease. </section> <section xml:id="rcm8224-sec-0002" numbered="no"> <title type="main">Methods >The method was developed using solid‐phase microextraction with Oasis?MAX μElution plates and ultra‐performance liquid chromatography/tandem mass spectrometry (UPLC/MS/MS). Electrospray ionization was performed in the negative mode (ESI?); the multiple reaction monitoring mode (MRM) was used. The development of the method included the optimization of the chromatographic conditions to achieve the separation of PGF2α and 8‐iso‐PGF2α as well as the optimization of the microextraction conditions of the analyte of interest in ovine and goat plasma. </section> <section xml:id="rcm8224-sec-0003" numbered="no"> <title type="main">Results >The developed method was validated with a calibration curve of plasma samples fortified with standards at five concentration levels in the range 49–639?pg/mL. The average recovery was 89% with a standard deviation of 10.73%. The inter‐day precision was evaluated, obtaining a coefficient of variance (CV) less than 15%. The limit of quantification was 20?pg/mL and the limit of detection was 10?pg/mL. 8‐iso‐PGF2a was determined in the plasma of 14 sheep and 20 goats of 5?months of age and 6 goats of 24?months of age. The concentrations found were 50–300?pg/mL. </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><abstract xmlns =“http://www.wiley.com/namespaces/wiley”type =“main”xml：lang =“en”> <section xml：id =“rcm8224-sec-0001”编号=“否” > <标题类型=“main”>基本原理</标题> >异丙醇8-ISO-PGF2α是细胞膜中脂质过氧化的生物标志物。为测量血浆总水平（酯化+自由）的8-ISO-PGF2α的方法必须是可再现的并且能够减少固相提取中的溶剂的使用。评估由于某些疾病或疾病产生的过量自由基而评估氧化应激。</ p> </ section> <sectoryed =“rcm8224-sec-0002”编号=“否” > <标题类型=“main”>方法</标题> >该方法是使用与绿洲的固相微萃取和超级性液相色谱/串联质谱（UPLC / MS / MS）开发的方法。电喷雾电离在负模式（ESI？）中进行;使用多反应监测模式（MRM）。该方法的发展包括优化色谱条件，以实现PGF2α和8-ISO-PGF2α的分离以及在绵羊和山羊血浆中的分析物的微萃取条件的优化。</ p> </第> <第XML：ID =“RCM8224-SEC-0003”编号=“否”> <标题类型=“main”>结果</ title> >通过强化等离子体样本的校准曲线验证开发方法在49-639℃的五个浓度水平下具有标准标准.Pg / ml。平均回收率为89％，标准差为10.73％。评估日内的常见精度，获得差异系数（CV）小于15％。定量限为20·pg / ml，检测限为10〜pg / ml。 8-ISO-PGF2A在14只羊的血浆中测定，5个月，5个月，6个月的6个月，24个月。发现的浓度为50-300？pg / ml。</ p> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-26627/'>《Rapid Communications in Mass Spectrometry: RCM》</a> <b style="margin: 0 2px;">|</b><span>2018年第19期</span><b style="margin: 0 2px;">|</b><span>共8页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Rodríguez Pati?o Gabriela&option=202" target="_blank" rel="nofollow">Rodríguez Pati?o Gabriela;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Castillo Rodríguez Miriam Aide&option=202" target="_blank" rel="nofollow">Castillo Rodríguez Miriam Aide;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ramírez Bribiesca Jacinto Efren&option=202" target="_blank" rel="nofollow">Ramírez Bribiesca Jacinto Efren;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ramírez Noguera Patricia&option=202" target="_blank" rel="nofollow">Ramírez Noguera Patricia;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Gonsebatt Bonaparte María Eugenia&option=202" target="_blank" rel="nofollow">Gonsebatt Bonaparte María Eugenia;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=López‐Arellano Raquel&option=202" target="_blank" rel="nofollow">López‐Arellano Raquel;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>National Autonomous University of MexicoCuautitlán Multidisciplinary Research Unit Cuautitlán Izcalli Edo. Mexico Mexico CP 54714;</p> <p>National Autonomous University of MexicoCuautitlán Multidisciplinary Research Unit Cuautitlán Izcalli Edo. Mexico Mexico CP 54714;</p> <p>Postgraduate College Livestock Program MontecilloTexcoco Edo. Mexico Mexico CP 56230;</p> <p>National Autonomous University of MexicoCuautitlán Multidisciplinary Research Unit Cuautitlán Izcalli Edo. Mexico Mexico CP 54714;</p> <p>National Autonomous University of Mexico Institute of Biomedical Genomic Medicine and Environmental Toxicology ResearchUniversity City Coyoacán Mexico City Mexico CP 04510;</p> <p>National Autonomous University of MexicoCuautitlán Multidisciplinary Research Unit Cuautitlán Izcalli Edo. Mexico Mexico CP 54714;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/1187.html" title="分析化学">分析化学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> </p> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704024020038.html">Development of a method for the determination of 8‐iso‐PGF2α in sheep and goat plasma using solid‐phase microextraction and ultra‐performance liquid chromatography/tandem mass spectrometry</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Rodríguez Pati?o Gabriela&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Rodríguez Pati?o Gabriela,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Castillo Rodríguez Miriam Aide&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Castillo Rodríguez Miriam Aide,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ramírez Bribiesca Jacinto Efren&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Ramírez Bribiesca Jacinto Efren,</a> <a href="/journal-foreign-26627/" target="_blank" rel="nofollow" class="tuijian_authcolor">Rapid Communications in Mass Spectrometry: RCM .</a> <span>2018</span><span>,第19期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：使用固相微萃取和超高效液相色谱/串联质谱法测定绵羊和山羊血浆中8-ISO-PGF2α的方法的研制</span> </p> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-foreign_detail_thesis/0204114845969.html">A novel magnetic multi-walled carbon nanotube-based magnetic solid-phase extraction combined with dispersive liquid–liquid microextraction method for the determination of four phenoxy carboxylic acid herbicides in food crops by using ultra-high performance liquid chromatography-tandem mass spectrometry</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Xucan Yuan&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Xucan Yuan,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Chu Liu&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Chu Liu,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Jing Zhao&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Jing Zhao,</a> <a href="/journal-foreign-19095/" target="_blank" rel="nofollow" class="tuijian_authcolor">Analytical methods .</a> <span>2018</span><span>,第26期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：新型磁性多壁碳纳米管为基础的磁性固相萃取-分散液-液微萃取-超高效液相色谱-串联质谱法测定粮食作物中的四种苯氧基羧酸类除草剂</span> </p> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704022625867.html">A novel magnetic multi-walled carbon nanotube-based magnetic solid-phase extraction combined with dispersive liquid-liquid microextraction method for the determination of four phenoxy carboxylic acid herbicides in food crops by using ultra-high performance liquid chromatography-tandem mass spectrometry</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yuan Xucan&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Yuan Xucan,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Liu Chu&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Liu Chu,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Zhao Jing&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Zhao Jing,</a> <a href="/journal-foreign-19088/" target="_blank" rel="nofollow" class="tuijian_authcolor">Analytical methods .</a> <span>2018</span><span>,第26期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：一种新型磁性多壁碳纳米管基磁性相萃取结合分散液 - 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A. </a> <span>2007</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：美国地质调查局有机地球化学研究组分析方法：采用固相萃取和液相色谱/串联质谱法测定水中溶解的异恶唑草酮及其顺序降解产物，二酮腈和苯甲酸</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_physical-testing-chemical-analysis-part-bchemical-analysis_thesis/0201212477212.html">毛细管固相微萃取-超高效液相色谱-串联质谱法测定血浆中麻醉精神药物</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=王毅&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 王毅</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=刘子秋&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,刘子秋</a> <span> <a href="/journal-cn-7677/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 理化检验-化学分册 </a> </span> <span> . 2015</span><span>,第002期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-cn_detail_thesis/0201295336556.html">分散微固相萃取-高效液相色谱-串联质谱法测定水样中3种氯霉素类和11种激素类药物残留</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=粟有志&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 粟有志</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=李艳美&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,李艳美</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=周均&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,周均</a> <span> <a href="/journal-cn-57080/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 分析科学学报 </a> </span> <span> . 2020</span><span>,第1期</span> </span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-journal-cn_journal-shanghai-jiaotong-university-medical-science_thesis/0201288799792.html">固相萃取联合高效液相色谱-串联质谱测定人血浆中肌苷浓度的方法学建立</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=金冠钦&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 金冠钦</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=孙黎&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,孙黎</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=夏玲红&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,夏玲红</a> <span> <a href="/journal-cn-6543/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 上海交通大学学报（医学版） </a> </span> <span> . 2021</span><span>,第003期</span> </span> </div> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-journal-cn_detail_thesis/0201297858935.html">固相萃取-高效液相色谱/串联质谱法测定大鼠血浆中二十二碳六烯酸</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=王丹&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 王丹</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=万慧慧&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,万慧慧</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张华&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,张华</a> <span> <a href="/journal-cn-57080/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 分析科学学报 </a> </span> <span> . 2015</span><span>,第1期</span> </span> </div> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-journal-cn_guangdong-chemical-industry_thesis/0201291704043.html">超交联多孔聚合物固相微萃取-高效液相色谱法测定环境水样中3种多环芳烃</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=苏美玲&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 苏美玲</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=刘亚敏&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,刘亚敏</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=黄贵琦&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,黄贵琦</a> <span> <a href="/journal-cn-9122/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 广东化工 </a> </span> <span> . 2021</span><span>,第020期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-40250_thesis/020222364857.html">低温冷冻及分散固相萃取净化-超高效液相色谱-串联质谱法测定植物油中104种农药残留</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=XU juan&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . XU juan</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=徐娟&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,徐娟</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=WANG Lan&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,WANG Lan</a> <span> <a href="/conference-cn-40250/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 第三届全国检验检测检疫学术报告会 </a> <span> <span> . 2015</span> </span> </div> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/academic-degree-domestic_mphd_thesis/020313810890.html">固相萃取-光化学荧光-高效液相色谱法测定血浆中叶酸含量</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=陈璇&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 陈璇</a> <span> . 2005</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/06120113766956.html">在线固相萃取、液相色谱-串联质谱法测定血浆中3种酪氨酸激酶抑制剂浓度的方法</a> <b>[P]</b> . <span> 中国专利： CN113777187A </span> <span> . 2021-12-10</span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06120113426329.html">一种固相萃取-高效液相色谱-串联质谱测定人体尿液中抗生素的方法</a> <b>[P]</b> . <span> 中国专利： CN113466381A </span> <span> . 2021-10-01</span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130406561184.html">QUICK METHOD FOR DETERMINING ORGANOMETALLIC COMPOUNDS IN ULTRA-TRACES, FROM SOIL SAMPLES, BY ULTRASONIC EXTRACTION-HEADSPACE-SOLID PHASE MICROEXTRACTION AND GAS CHROMATOGRAPHY COUPLED WITH MASS SPECTROMETRY (): SURFACE WATER, SOIL, AIR, VEGETATION</a> <b>[P]</b> . <span> 外国专利：  RO132682A2 </span> <span> . 2018-06-29</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：超声萃取-顶空固相微萃取-质谱联用气相色谱法快速测定土壤样品中痕量有机物的快速方法（）：地表水，土壤，空气，植被 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130419686825.html">AN INTEGRATED SOLID PHASE EXTRACTION COUPLED ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (SPE-UPLC-MS) METHOD FOR THE PROFILING OF DXP METABOLITES AND SYSTEM DIAGNOSTICS OF DXP PATHWAY</a> <b>[P]</b> . <span> 外国专利：  WO2013133772A1 </span> <span> . 2013-09-12</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：固相萃取-超高效液相色谱-质谱联用（SPE-UPLC-MS）进行DXP代谢产物鉴定和DXP通路的系统诊断 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130430416870.html">Quantitative determination of Risedronate in urine by SPE - LC - MS - MS. Solid phase extraction - High Performance Liquid Chromatography - mass spectrometry.</a> <b>[P]</b> . <span> 外国专利：  AR065598A1 </span> <span> . 2009-06-17</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过SPE-LC-MS-MS定量测定尿中的Riseronate。固相萃取-高效液相色谱-质谱。 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon clearfix" style="margin-bottom: 10px;display:none;" > </div> </div> </div> <div id="thesis_get_original1" class="downloadBth" style="bottom: 19px;z-index: 999;" onclick="ywcd('0704024020038','4',7,2,1,'',this,24)" class="delivery" prompt="010401" title="通过人工服务将文献原文发送至邮箱" >获取原文</div> <div class="journalsub-pop-up" style="display: none"> 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