Mesoporous Silica Nanoparticles: A Versatile Platform for Biomedical Applications

摘要

Background: Nanotechnology-based drug delivery approach has emerged as a promisingfield, where different kinds of formulations are developed for therapeutic applications. Inflowing ofnanomedicine developed through various biomaterials appears to be a game changer in the domain ofpharmaceutical and biotechnological industries. Nanomedicines propose to overcome the major constraintsof conventional medicine of low solubility and stability, non-adequate pharmacokinetic profilesand side effects.Objectives: Mesoporous Silica Nanoparticles (MSNs) have garnered significant attention in biomedicalapplications for its multifunctionality. The porous structure of MSNs provides the opportunity forheavy drug loading, controlled release and ligand functionality. From last decades, a lot of interest hasbeen generated owing to the better drug delivery attributes of MSNs to introduce unique biologicaleffects for its suitable therapeutic application.Methods: The review article gives an insight into the current advancement of usage of MSNs in drugdelivery for cancer, non-cancer and biosensors based biomedical applications along with technologythat is protected by patents.Conclusion: The future success of MSNs is widened because of their valuable characteristic thateasily combines with various functionalities which would display enormous potential translationalpossibilities.