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A novel surgical technique for implanting a new electrostimulation system for treating female overactive bladder: a preliminary report.

机译:植入新的电刺激系统以治疗女性膀胱过度活动症的新型外科手术技术:初步报告。

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摘要

There are three interesting but diverse topics in this section. Authors from Tel-Aviv and Capetown describe a novel surgical technique for implanting a new electrostimulation system for treating overactive bladder in the female. This is followed by a classification of symptomatic nocturia from Japan, which also looks at the distribution of nocturia, with special attention to duration of time in bed. Finally, there is an interesting paper on the association between congenital adrenal hyperplasia and LUTS. OBJECTIVE To assess the results of peripheral electrostimulation of pelvic floor muscles in patients with overactive bladder (OAB) symptoms, and to describe a novel surgical technique for inserting a specially designed implantable electrostimulator which can deliver different forms of muscle stimulation through a para-urethral electrode. PATIENTS AND METHODS The study included seven women with OAB (mean age 59 years) who had frequency (including nocturia), urgency and urge incontinence for >/= 1 year, and in whom conventional treatment failed. The antepubic technique was used to implant the electrostimulator and a para-urethral electrode. The patients' urinary symptoms and quality of life (King's College Hospital incontinence questionnaire) were compared before and after surgery, and possible complications monitored. RESULTS The mean (range) follow-up was 14.5 (13-17) months in six and 10 months in the seventh patient (stimulator removed because of infection). The mean (range) frequency of 15 (13-23) voids/24 h before surgery decreased to 9 voids/24 h (i.e. by 40%) afterward. All patients had leakage episodes because of urgency (4-15 times/day) before surgery, which ceased in five afterward; these patients used no further pads. In the remaining two patients urgency incontinence continued after surgery, but with significantly fewer leakage episodes, from 15 and 12 per day before to 6.7 and 4 afterward, respectively. The mean degree of urgency (graded 0-3) decreased from 2 to 1.4 after surgery, and quality of life improved significantly. Urodynamic studies showed a greater mean maximum detrusor capacity, from 135 mL before to 189 mL after implanting the stimulator. CONCLUSIONS The good results (over a follow-up of 1 year) in patients with OAB symptoms treated by the present electrostimulator should encourage further clinical studies in such patients. A trial to evaluate the efficacy of pelvic floor muscle electrostimulation in a broad spectrum of diseases of the lower urinary tract causing symptoms similar to OAB has been started.
机译:本节包含三个有趣但多样的主题。来自特拉维夫和开普敦的作者描述了一种新颖的外科手术技术,用于植入新的电刺激系统来治疗女性膀胱过度活动症。其次是来自日本的症状性夜尿症的分类,该分类法还关注夜尿症的分布,并特别注意卧床时间。最后,关于先天性肾上腺皮质增生与LUTS之间的关系有一篇有趣的论文。目的评估膀胱过度活动症(OAB)症状患者骨盆底肌肉周围电刺激的结果,并描述一种新颖的外科手术技术,用于插入专门设计的可植入电刺激器,该电刺激器可通过尿道旁电极提供不同形式的肌肉刺激。患者与方法该研究纳入了7例OAB(平均年龄59岁)的妇女,其频率(包括夜尿症),尿急和急迫性尿失禁> / = 1年,并且常规治疗失败。耻骨前技术用于植入电刺激器和尿道旁电极。在手术前后比较患者的尿路症状和生活质量(国王大学医院失禁问卷),并监测可能的并发症。结果第七例患者的平均(范围)随访为6个月和10个月,分别为14.5(13-17)个月(由于感染而去除了刺激物)。手术前24小时15(13-23)个空隙的平均(范围)频率下降到术后24小时9个空隙(即40%)。所有患者由于手术前的紧急性(4-15次/天)而出现渗漏事件,此后五次停止。这些患者不再使用垫子。其余两名患者术后急迫性尿失禁继续,但渗漏次数明显减少,分别从之前的每天15次和每天12次到之后的6.7次和之后的4次。手术后的平均紧迫度(0-3级)从2降低至1.4,生活质量显着改善。尿动力学研究显示更大的平均最大逼尿肌容量,从植入刺激物之前的135 mL到植入刺激物之后的189 mL。结论通过本电刺激器治疗的具有OAB症状的患者的良好结果(超过1年的随访)应鼓励对该患者进行进一步的临床研究。已经开始了一项试验,以评估盆底肌电刺激在下尿路引起的类似于OAB症状的多种疾病中的疗效。

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