MnFe2O4 magnetic nanoparticles modified with chitosan polymeric and phosphotungstic acid as a novel and highly effective green nanocatalyst for regio- and stereoselective synthesis of functionalized oxazolidin-2-ones

摘要

A novel magnetically recoverable acid nanocatalyst, MnFe2O4/chitosan/phosphotungstic acid (MnFe2O4@CS@PTA), was successfully synthesized. The synthesized nanoparticle was studied as the heterogenous nanocatalyst to prepare the functionalized oxazolidin-2-ones as versatile chiral synthons in asymmetrically synthesizing the compounds with biological activity through the reaction of alpha-epoxyketones with urea and thiourea.