Synthesis of cinnamyl substituted dihydrofuranones by the Heck cross-coupling reaction

摘要

The Heck cross-coupling of 3-allyldihydrofuran-2(3H)-ones with aryl bromides [Pd(OAc)(3), P(o-Tol)(3)] afforded the corresponding 3-cinnamyl derivatives. The structure of the products was confirmed by NMR spectroscopy, mass spectrometry and X-ray diffraction.