Rapid and Diversity-Oriented Construction of Extended n-Electron Systems Using Double Mizoroki-Heck Reaction and Double Hiyama Cross-Coupling Reaction

摘要

A novel strategy for the rapid and diversity-oriented construction of extended pi-electron systems,which utilizes dimethyl(2-pyrimidyl)vinylsilane as an unprecedented type of trifunctional platform,is described.With the emergence of many interesting properties of extended n-electron systems,efficient and rapid construction of such systems has become increasingly important in the field of material science.However,until very recently,chemists had to rely on a time-consuming empirical identification process for lead-structure discovery and optimization because structure-property relationships are often not predictable in material science.To date the power of combinatorial chemistry,which has already become a major methodology for drug discovery process in pharmaceutical science,have galvanized chemists to take such an approach in the field of material science.