Drug resistance profile and molecular characterization of extended spectrum beta-lactamase (ES beta L)-producing Pseudomonas aeruginosa isolated from burn wound infections. Essential oils and their potential for utilization

摘要

Objectives: Pseudomonas aeruginosa producing extended spectrum beta-lactamase (ES beta L) enzyme had the ability for antimicrobial resistance mechanisms and its multidrug-resistant (MDR) phenotype, has been increasingly reported as a major clinical concern worldwide. The aim of this study was to (i) characterize ES beta L-producing MDR P. aeruginosa isolated from burn wound infections phenotypically and molecularly, (ii) evaluate the antibacterial activity of some essential oils (EOs) against selected ES beta L-producing drug resistant P. aeruginosa and (iii) characterize a promising EO.