Survival analysis for male ductal and lobular breast cancer patients with different stages

摘要

Aim: We aimed to investigate risk factors and current treatment effects in male breast cancer patients. Methods: Kaplan-Meier plot, log-rank test, COX model, nomograms and propensity score matching were used. Results: Among stage I-III patients, surgery was associated with better prognosis. In subgroup analysis, performing surgery and no radiation or chemotherapy led to worse prognosis in research group. Among stage IV patients, chemotherapy correlated with better prognosis and radiation led to better breast cancer-specific survival. In addition, brain and liver metastasis correlated with worse prognosis; and lung correlated with worse breast cancer-specific survival. Conclusion: For stage I-III patients, surgery and chemotherapy were recommended. And not applying radiation or chemotherapy could be carefully considered for ER(+) HER-2(-) patients. For stage IV patients, chemotherapy and radiation were commended.