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首页> 外文期刊>Gut: Journal of the British Society of Gastroenterology >Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer
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Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer

机译:作为治疗肝癌的溶血性reovirus作为肝癌的组合抗病毒和抗肿瘤剂

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摘要

Objective Oncolytic viruses (OVs) represent promising, proinflammatory cancer treatments. Here, we explored whether OV-induced innate immune responses could simultaneously inhibit HCV while suppressing hepatocellular carcinoma (HCC). Furthermore, we extended this exemplar to other models of virus-associated cancer.
机译:目的缺课病毒(OVS)代表有前途,促炎癌症治疗方法。 在这里,我们探讨了ov-诱导的先天免疫应答是否可以同时抑制HCV,同时抑制肝细胞癌(HCC)。 此外,我们将此示例扩展到其他病毒相关癌症的模型。

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  • 作者单位

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Ohio State Univ Ctr Comprehens Canc Columbus OH 43210 USA;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Natl Inst Infect Dis Dept Virol 2 1-23-1 Toyama Tokyo Japan;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Inst Canc Res Dept Mol Med London England;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

    Inst Canc Res Dept Mol Med London England;

    Univ Leeds Leeds Inst Canc &

    Pathol LICAP St James Univ Hosp Fac Med &

    Hlth Leeds W Yorkshire;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 消化系及腹部疾病;
  • 关键词

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