Insulin delivery and nocturnal glucose control in children and adolescents with type 1 diabetes

Tauschmann Martin; Hovorka Roman

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Insulin delivery and nocturnal glucose control in children and adolescents with type 1 diabetes

机译：儿童和青少年胰岛素递送和夜间葡萄糖对照组1型糖尿病

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Introduction: Nocturnal glucose control remains challenging in children and adolescents with type 1 diabetes due to highly variable overnight insulin requirements. The issue may be addressed by glucose responsive insulin delivery based on real-time continuous glucose measurements.

机译：简介：由于高度可变的胰岛素要求，夜间葡萄糖控制仍然具有1型糖尿病的儿童和青少年挑战。该问题可以通过基于实时连续葡萄糖测量的葡萄糖响应性胰岛素递送来解决。

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《Expert opinion on drug delivery 》 |2017年第12期| 共11页
作者
Tauschmann Martin; Hovorka Roman;
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作者单位

Univ Cambridge Wellcome Trust MRC Inst Metab Sci Cambridge England;

Univ Cambridge Wellcome Trust MRC Inst Metab Sci Cambridge England;

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原文格式 PDF
正文语种 eng
中图分类药学 ;
关键词
Threshold-based insulin interruption; low glucose suspension; predictive low glucose suspension; artificial pancreas; closed-loop system; type 1 diabetes; control algorithm; insulin pump; continuous glucose monitor;

机译：基于阈值的胰岛素中断;低葡萄糖悬浮液;预测低葡萄糖悬浮液;人工胰腺;闭环系统;1型糖尿病;控制算法;胰岛素泵;连续葡萄糖显示器;

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专利

1. Insulin delivery and nocturnal glucose control in children and adolescents with type 1 diabetes [J] . Tauschmann Martin, Hovorka Roman Expert opinion on drug delivery . 2017 ,第7a12期

机译：儿童和青少年胰岛素递送和夜间葡萄糖对照组1型糖尿病
2. Nocturnal glucose control and free insulin levels in children with type 1 diabetes by use of the long-acting insulin HOE 901 as part of a three-injection regimen (letter) [J] . Mohn A, Strang S, Wernicke Panten-K, Diabetes care . 2000 ,第4期

机译：通过使用长效胰岛素HOE 901作为三剂治疗方案的一部分，对1型糖尿病儿童进行夜间血糖控制和游离胰岛素水平（字母）
3. Outpatient overnight glucose control with dual-hormone artificial pancreas, single-hormone artificial pancreas, or conventional insulin pump therapy in children and adolescents with type 1 diabetes: an open-label, randomised controlled trial [J] . Haidar Ahmad, Legault Laurent, Matteau-Pelletier Laurence, The lancet. Diabetes & endocrinology. . 2015 ,第8期

机译：1型糖尿病儿童和青少年的双激素人工胰腺，单激素人工胰腺或常规胰岛素泵治疗的门诊过夜血糖控制：一项开放标签，随机对照试验
4. Intelligent control of glucose concentration based on an implantable insulin delivery system for type I diabetes [C] . Al-Fandi Mohamed, Jaradat Mohammad A., Sardahi Yousef, 2011 IEEE Jordan Conference on Applied Electrical Engineering and Computing Technologies . 2011

机译：基于可植入式I型糖尿病胰岛素输送系统的葡萄糖浓度智能控制
5. Evaluating Hypoglycemic Risk of Two Basal Insulin Delivery Methods for Type 1 Diabetes: A Comparison of Tresiba Insulin Against Continuous Subcutaneous Insulin Infusion Using Data from Continuous Glucose Monitors [D] . Lane, Benjamin. 2020

机译：评估1型糖尿病两种基础胰岛素递送方法的低血糖风险：使用来自连续葡萄糖监测器的数据进行TRESIBA胰岛素对连续皮下胰岛素输注的比较
6. Insulin delivery and nocturnal glucose control in children and adolescents with type 1 diabetes [O] . Martin Tauschmann, Roman Hovorka -1

机译：1型糖尿病儿童和青少年的胰岛素输送和夜间血糖控制
7. Multicenter closed-loop insulin delivery study points to challenges for keeping blood glucose in a safe range by a control algorithm in adults and adolescents with type 1 diabetes from various sites. [O] . Zisser H, Renard E, Kovatchev B, 2014

机译：多中心闭环胰岛素输送研究指出了通过控制算法将血糖控制在安全范围内的挑战，该算法适用于来自不同地点的1型糖尿病的成年人和青少年。

Insulin delivery and nocturnal glucose control in children and adolescents with type 1 diabetes

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