Update on the role and therapeutic potential of polycomb repressive complexes in (biliary tract) cancer

Daniel Neureiter; Tobias Kiesslich; Markus Ritter; Christian Mayr

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Update on the role and therapeutic potential of polycomb repressive complexes in (biliary tract) cancer

机译：关于（胆道）癌症中Polycomb压抑复合物的作用和治疗潜力的更新

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In a recent review we discussed the role of the polycomb repressive complexes (PRC) 1 and 2 in biliary tract cancer (BTC).Both, the PRC1 and 2 are multi-protein complexes that epigenetically regulate gene expression by specific histone modifications associated with transcriptional silencing

机译：在最近的综述中，我们讨论了多元抑制复合物（PRC）1和2在胆道癌症（BTC）中的作用.both，PRC1和2是通过与转录相关的特异性组蛋白修饰进行表现出对基因表达的多蛋白质复合物沉默

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《Expert opinion on therapeutic targets》 |2018年第6期|共3页
作者
Daniel Neureiter; Tobias Kiesslich; Markus Ritter; Christian Mayr;
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Institute of Pathology Paracelsus Medical University/Salzburger Landeskliniken Salzburg Austria;

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正文语种 eng
中图分类药学;
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专利

1. Update on the role and therapeutic potential of polycomb repressive complexes in (biliary tract) cancer [J] . Daniel Neureiter, Tobias Kiesslich, Markus Ritter, Expert opinion on therapeutic targets . 2018,第1a6期

机译：关于（胆道）癌症中Polycomb压抑复合物的作用和治疗潜力的更新
2. PI3K-mTOR pathway identified as a potential therapeutic target in biliary tract cancer using a newly established patient-derived cell panel assay [J] . Sakamoto Yasunari, Yamagishi Seri, Tanizawa Yoshinori, Japanese journal of clinical oncology. . 2018,第4期

机译：使用新建立的患者衍生的细胞面板测定鉴定为胆囊癌的潜在治疗靶标的PI3K-MTOR途径
3. Biliary Tract Cancer: State of the Art and potential role of DNA Damage Repair [J] . Lamarca Angela, Barriuso Jorge, McNamara Mairead G., Cancer Treatment Reviews . 2018,第期

机译：胆道癌症：现有技术和DNA损伤修复的潜在作用
4. The Role of International Classification of Diseases in Assessment of Patients with Biliary Tract Disease [C] . Haris PANDZA, Izet MASIC, Reuf KARABEG, Medical Informatics in Europe Conference. . 2009

机译：国际疾病分类对胆道疾病患者的作用
5. Analysis of Single Circulating Tumor Cells (CTCS) to Infer Phenotype and Genome Changes in Response to Therapeutic Pressures in Biliary Tract Cancer [D] . Reduzzi, Carolina. 2020

机译：对单循环肿瘤细胞（CTC）推断表型和基因组变化的响应胆道癌中的治疗压力
6. DNA methylation reprogramming in cancer: Does it act by re-configuring the binding landscape of Polycomb repressive complexes? [O] . James P Reddington, Duncan Sproul, Richard R Meehan -1

机译：癌症中的DNA甲基化重编程：它是否通过重新配置Polycomb阻遏复合物的结合态起作用？
7. Update on the role and therapeutic potential of polycomb repressive complexes in (biliary tract) cancer [O] . Daniel Neureiter, Tobias Kiesslich, Markus Ritter, 2017

机译：（胆道）癌症中Polycomb压抑复合物的作用和治疗潜力的更新

Update on the role and therapeutic potential of polycomb repressive complexes in (biliary tract) cancer

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