Melphalan hydrochloride for the treatment of multiple myeloma

Esma Fabrizio; Salvini Marco; Troia Rossella; Boccadoro Mario; Larocca Alessandra; Pautasso Chiara

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Melphalan hydrochloride for the treatment of multiple myeloma

机译：盐酸莫尔兰甘露盐，用于治疗多发性骨髓瘤

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Introduction: Multiple myeloma (MM) is an incurable disease characterized by clonal plasma cell proliferation and overproduction of monoclonal paraprotein, hypercalcemia, renal failure, anemia, osteolytic bone lesions, and infections.

机译：介绍：多种骨髓瘤（mm）是一种可治区疾病，其特征在于克隆血浆细胞增殖和过量的单克隆帕拉奇蛋白，高钙血症，肾功能衰竭，贫血，骨质疏松骨病变和感染。

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来源
《Expert opinion on pharmacotherapy 》 |2017年第12期| 共10页
作者
Esma Fabrizio; Salvini Marco; Troia Rossella; Boccadoro Mario; Larocca Alessandra; Pautasso Chiara;
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作者单位

Azienda Osped Univ Citta Salute &

Sci Torino Div Hematol Myeloma Unit Via Genova 3 I-10126;

Azienda Osped Univ Citta Salute &

Sci Torino Div Hematol Myeloma Unit Via Genova 3 I-10126;

Azienda Osped Univ Citta Salute &

Sci Torino Div Hematol Myeloma Unit Via Genova 3 I-10126;

Azienda Osped Univ Citta Salute &

Sci Torino Div Hematol Myeloma Unit Via Genova 3 I-10126;

Azienda Osped Univ Citta Salute &

Sci Torino Div Hematol Myeloma Unit Via Genova 3 I-10126;

Azienda Osped Univ Citta Salute &

Sci Torino Div Hematol Myeloma Unit Via Genova 3 I-10126;

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原文格式 PDF
正文语种 eng
中图分类药学 ;
关键词
Melphalan; multiple myeloma; pharmacodynamics; pharmacokinetics; chemistry; combination;

机译：Melphalan;多发性骨髓瘤;药效学;药代动力学;化学;组合;

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专利

1. Melphalan hydrochloride for the treatment of multiple myeloma [J] . Esma Fabrizio, Salvini Marco, Troia Rossella, Expert opinion on pharmacotherapy . 2017 ,第7a12期

机译：盐酸莫尔兰甘露盐，用于治疗多发性骨髓瘤
2. The Cost-Effectiveness of Initial Treatment of Multiple Myeloma in the U.S. With Bortezomib Plus Melphalan and Prednisone Versus Thalidomide Plus Melphalan and Prednisone or Lenalidomide Plus Melphalan and Prednisone With Continuous Lenalidomide Maintenance Treatment [J] . Louis P. Garrison, Si-Tien Wang, Hui Huang, The oncologist . 2013 ,第1期

机译：硼替佐米联合美法仑和泼尼松对沙利度胺加美法仑和泼尼松或来那度胺联合美法仑和泼尼松联合来那度胺持续维持治疗的美国多发性骨髓瘤初始治疗的成本-效果
3. Bortezomib, thalidomide, dexamethasone induction therapy followed by melphalan, prednisolone, thalidomide consolidation therapy as a first line of treatment for patients with multiple myeloma who are non-transplant candidates: results of the Korean Multiple Myeloma Working Party (KMMWP). [J] . Eom HS, Kim YK, Chung JS, Annals of hematology . 2010 ,第5期

机译：硼替佐米，沙利度胺，地塞米松诱导治疗，美法仑，泼尼松龙，沙利度胺巩固治疗作为非移植候选多发性骨髓瘤患者的第一线治疗方法：韩国多发性骨髓瘤工作组（KMMWP）的结果。
4. Deep learning based risk stratification for treatment management of multiple myeloma with sequential MRI scans [C] . Chuan Zhou, Heang-Ping Chan, Lubomir M Hadjiiski, Conference on Medical Imaging: Computer-Aided Diagnosis . 2021

机译：基于深度学习的序列MRI扫描治疗骨髓瘤治疗管理的风险分层
5. Heparanase drives the aggressive myeloma phenotype: Preclinical development of a heparanase inhibitor for the treatment of multiple myeloma. [D] . Ritchie, Joseph P. 2010

机译：乙酰肝素酶驱动侵袭性骨髓瘤表型：用于治疗多发性骨髓瘤的乙酰肝素酶抑制剂的临床前开发。
6. The Cost-Effectiveness of Initial Treatment of Multiple Myeloma in the U.S. With Bortezomib Plus Melphalan and Prednisone Versus Thalidomide Plus Melphalan and Prednisone or Lenalidomide Plus Melphalan and Prednisone With Continuous Lenalidomide Maintenance Treatment [O] . Louis P. Garrison Jr., Si-Tien Wang, Hui Huang, 2013

机译：硼替佐米加美法仑和泼尼松与沙利度胺加美法仑和泼尼松或来那度胺加美法仑和泼尼松联合来那度胺持续维持治疗的美国多发性骨髓瘤的初始治疗的成本效益
7. Natural interferon-alpha in combination with melphalan/prednisone versus melphalan/prednisone in the treatment of multiple myeloma stages II and III: a randomized study from the Myeloma Group of Central Sweden [O] . A Osterborg, M Bjorkholm, M Bjoreman, 1993

机译：天然干扰素-α-与Melphalan /泼尼松的组合相对于Melphalan /泼尼松，治疗多发性骨髓瘤阶段II和III：瑞典中部骨髓瘤组的随机研究

Melphalan hydrochloride for the treatment of multiple myeloma

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