ERK pathway activation contributes to the tumor-promoting effects of hepatic stellate cells in hepatocellular carcinoma

Xie Yu-Xiao; Liao Rui; Pan Long; Du Cheng-You

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ERK pathway activation contributes to the tumor-promoting effects of hepatic stellate cells in hepatocellular carcinoma

机译：ERK途径激活有助于肝星状细胞在肝细胞癌中的肿瘤促进作用

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Background Activated hepatic stellate cell (aHSC) play a critical role in hepatocellular carcinoma (HCC) progression crosstalking with cancer cell via various signaling pathways. The aim of our study is to explore the tumor-promoting effects of aHSCs on HCC via ERK pathway.

机译：背景技术活化的肝星状细胞（AHSC）通过各种信号通路在肝细胞癌（HCC）进展中发挥着关键作用。我们的研究目的是通过ERK途径探讨AHSCS对HCC的肿瘤促进作用。

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《Immunology Letters 》 |2017年第2017期| 共8页
作者
Xie Yu-Xiao; Liao Rui; Pan Long; Du Cheng-You;
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作者单位

Chongqing Med Univ Affiliated Hosp 1 Dept Hepatobiliary Surg 1 Yixueyuan Rd Chongqing 400016;

Chongqing Med Univ Affiliated Hosp 1 Dept Hepatobiliary Surg 1 Yixueyuan Rd Chongqing 400016;

Chongqing Med Univ Affiliated Hosp 1 Dept Hepatobiliary Surg 1 Yixueyuan Rd Chongqing 400016;

Chongqing Med Univ Affiliated Hosp 1 Dept Hepatobiliary Surg 1 Yixueyuan Rd Chongqing 400016;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学 ;
关键词
Hepatic stellate cell; Epithelial mesenchymal transition; Liver cancer; Mitogen-activated protein kinase;

机译：肝星状细胞;上皮间充质转换;肝癌;丝裂剂活化蛋白激酶;

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专利

1. ERK pathway activation contributes to the tumor-promoting effects of hepatic stellate cells in hepatocellular carcinoma [J] . Xie Yu-Xiao, Liao Rui, Pan Long, Immunology Letters . 2017 ,第期

机译：ERK途径激活有助于肝星状细胞在肝细胞癌中的肿瘤促进作用
2. Hepatic Stellate Cells Contribute to the Tumor Malignancy of Hepatocellular Carcinoma Through the IL-6 Pathway [J] . Iwahasi Shuichi, Rui Feng, Morine Yuji, Anticancer Research: International Journal of Cancer Research and Treatment . 2020 ,第2期

机译：肝星状细胞通过IL-6途径有助于肝细胞癌的肿瘤恶性肿瘤
3. Soluble FGL2, a novel effector molecule of activated hepatic stellate cells, regulates T-cell function in cirrhotic patients with hepatocellular carcinoma [J] . Ying Sun, Dong Xi, Wen Ding, Hepatology international . 2014 ,第4期

机译：可溶性FGL2是活化的肝星状细胞的新型效应分子，可调节肝细胞癌肝硬化患者的T细胞功能
4. A complex network of intra- and intercellular mediators regulate cellular activation and transdifferentiation of hepatic stellate cells [C] . R. WEISKIRCHEN, E. BORKHAM-KAMPHORST, S. K. MEURER, Falk Symposium . 2008

机译：内细胞间介质的复杂网络调节肝星状细胞的细胞活化和转染细胞
5. Effects of S-adenosyl-L-methionine on collagen expression in activated hepatic stellate cells. [D] . Thompson, Kyle James. 2009

机译：S-腺苷-L-蛋氨酸对活化的肝星状细胞胶原蛋白表达的影响。
6. Mannan-binding lectin suppresses growth of hepatocellular carcinoma by regulating hepatic stellate cell activation via the ERK/COX-2/PGE2 pathway [O] . Junru Li, Huifang Li, Yu Yu, 2019

机译：甘露聚糖结合凝集素通过通过ERK / COX-2 / PGE2途径调节肝星状细胞的活化来抑制肝癌的生长
7. Mannan-binding lectin suppresses growth of hepatocellular carcinoma by regulating hepatic stellate cell activation via the ERK/COX-2/PGE2 pathway [O] . Junru Li, Huifang Li, Yu Yu, 2018

机译：甘露结合凝集素通过ERK / COX-2 / PGE2途径调节肝星状细胞活化来抑制肝细胞癌的生长

ERK pathway activation contributes to the tumor-promoting effects of hepatic stellate cells in hepatocellular carcinoma

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