P-671: Are sarcopenia and frailty associated with distal radius fracture in older people?

摘要

Introduction: Sarcopenia, which is described as loss of muscle mass and function, worsens daily living activities of older people. Sarcopenia is a component of frailty that causes falls and fractures in older people. The aim of this study was to evaluate sarcopenia and frailty status of elder people with distal radius fracture (DRF) and compare with age and sex matched controls without DRF. Methods: We recruited 27 patients with DRF and 28 controls without DRF. All participitants were 65 years and over. The sarcopenia was diagnosed according to definition of European Working Group on Sarcopenia in Older People. Frailty was assessed by Fried frailty index. Comprehensive geriatric assessment was performed and body mass index, albumin, calcium, phosphorus and vitamin D levels were analyzed in whole group. Osteoporosis was diagnosed as femur neck, femur total and lumber total T scores were less than - 2.5 SD from the normal range of youngs. All data were analyzed by SPSS 21.0 programme. Results: Seven of total 27 patients with DRF and 8 of total 28 controls without DRF were male. Median ages were 70 years and 71 years (min: 65, max: 87 in both) in DRF patients and controls respectively. Sarcopenia and frailty status were similar between groups (p = 0.48, p = 0.64). The prefrail phenotype was higher in patients with DRF (p = 0.03). The prefrail phenotype was an independent variable predicting distal radius fracture in logistic regression models. There was no significant difference in sarcopenia parameters including skeletal muscle mass index, 4-meter gait speed and grip strength between the groups. Conclusions: This study showed that the rate of prefrail phenotype was higher in patients with DRF and prefrail phenotype was an independent variable predicting DRF whereas sarcopenia and frailty status were similar between groups.