Mozart's music in children with drug-refractory epileptic encephalopathies: Comparison of two protocols

摘要

In this prospective, randomized, open label study, we compared the effect on seizure recurrence and quality-of-life parameters, of two different protocols of music therapy in children and adolescents with refractory epileptic encephalopathies. Nine out of 19 patients (13 males and 6 females, aged between 1 and 24 years) were randomized to listen to Mozart's sonata in D major for two pianos K448 for 2 h/day for 2 weeks; other 10 children were randomized on a set of Mozart's compositions.