Enhanced performance of a hyperbranched rolling circle amplification based electrochemiluminescence aptasensor for ochratoxin A using an electrically heated indium tin oxide electrode

摘要

A promising and novel electrochemiluminescence (ECL) aptasensor equipped with an electrically heated indium tin oxide (ITO) electrode was constructed. Temperature control was achieved by heating the ITO electrode, avoiding the tedious operation and substantial increase in noise experienced when heating the bulk solution. Using the heated ITO electrode, an order of magnitude improvement in ECL sensitivity was obtained by operating the electrode at 65 degrees C compared to 25 degrees C, and this can be used to further enhance the performance of the biosensor.