Synthesis and biological assay of O,O-diaryl O-2-chloroethyl phosphorothionates against rhizoctonia solani and sclerothium rolfsii

摘要

Twenty new O,O-diaryl O-2-chloroethyl phosphorothionates, having different phenyl substitutions, have been synthesized and characterized by physico-chemical techniques. The compounds have been evaluated for their fungicidal activity against two phytopathogenic fungi viz., Rhizoctonia solani and Sclerotium rolfsii. The most active compounds are O,O-di(pentachlorophenyl) O-2-chloroethyl phosphorothionate (ED_(50) = 0.419 mgmL~(-1)) and O,O-di(2-methylphenyl) O-2-chloroethyl phosphorothionate (ED_(50) = 0.426 mg mL~(-1)) against R. solani and S. rolfsii respectively.