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首页> 外文期刊>Indian journal of clinical biochemistry: IJCB >Blood Lead Levels in Occupationally Exposed Workers Involved in Battery Factories of Delhi-NCR Region: Effect on Vitamin D and Calcium Metabolism
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Blood Lead Levels in Occupationally Exposed Workers Involved in Battery Factories of Delhi-NCR Region: Effect on Vitamin D and Calcium Metabolism

机译:血铅水平在职业暴露工人参与Delhi-NCR地区的电池厂:对维生素D和钙代谢的影响

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Workers involved in battery manufacturing or recycling factories are occupationally exposed to high concentrations of lead. In humans, lead can cause a wide range of biological effects depending upon the level and duration of exposure. The purpose of this study was to find out the blood lead levels (BLL) in occupationally exposed workers involved in battery industry in Delhi NCR region and to study whether lead affected the vitamin?D?(vit?D) and calcium metabolism. For this study 100 occupationally lead-exposed battery workers (LEBW) and 100 non-lead exposed controls (NLEC) were recruited. BLL were measured using inductively coupled plasma optical emission?spectrometer?(ICP-OES) technique while ELISA was performed to quantify the serum vit D levels in the study subjects. Routine biochemical parameters were measured by chemistry autoanalyzers. Statistical analysis was done using appropriate statistical tools. Results showed that BLL were significantly higher in LEBW as compared to NLEC (p?
机译:参与电池制造或回收工厂的工人被职业上暴露于高浓度的铅。在人类中,铅可根据暴露的水平和持续时间引起广泛的生物学效应。本研究的目的是在德里NCR地区的电池行业职业暴露工人中找到血铅水平(BLL),并研究铅是否影响维生素?(VIT'D)和钙代谢。对于这项研究,招聘了100职业领先的铅暴露的电池工人(LEBW)和100名非领先暴露的控制(NLEC)。使用电感耦合等离子体光发射测量BLLΔ(ICP-OES)技术,同时进行ELISA以量化研究受试者的血清VIT D水平。通过化学自动分析仪测量常规生化参数。使用适当的统计工具进行统计分析。结果表明,与NLEC相比,LEBW的BL1显着高(P?<?0.0001)。与对照相比,电池工人血清维生素D,钙和磷水平显着下降(P?<0.005)。 Spearman的等级相关分析显示BLL与血清维生素D和钙水平的显着负相关。在BLL和铅暴露的持续时间之间观察到显着的正相关性。即使在调整吸烟状态后,BLL和VIT D之间也观察到弱负相关。总之,本研究表明,较高的BLL显着改变了VIT D和钙代谢。

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