Effects of sample handling on plasma adrenocorticotrophic hormone (ACTH) stability in horses with normal and elevated ACTHconcentrations.

摘要

Basal ACTH concentration is recommended to diagnose pituitary pars intermedia dysfunction (PPID); however, previous studies have questioned accuracy when sample handling is less than ideal.Objective: to describe the effects on ACTH concentration and subsequent diagnosis of PPID after exposure of samples to various temperatures, separation techniques and storage conditions.