ESR2 Genetic Variants and Combined Oral Contraceptive Use Associated with the Risk of Stroke

Xu Zhenlin; Li Ying; Huang Xiaoping; Shen Wei; Bai Jianling; Shen Chong; Zhao Yang

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ESR2 Genetic Variants and Combined Oral Contraceptive Use Associated with the Risk of Stroke

机译：ESR2遗传变异和组合口服避孕药与中风风险相关

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Background and Aim. There is accumulating evidence suggesting an important role of estrogen receptor-beta in the development of cardiovascular disease. The present study aims to investigate the relationship of estrogen receptor beta gene (ESR2) polymorphisms with stroke risk in Chinese women, and further evaluate the gene-environment interaction of ESR2 and combined oral contraceptive (COC) use on stroke risk.

机译：背景和目标。积累了证据表明雌激素受体-β在心血管疾病发展中的重要作用。本研究旨在探讨雌激素受体β基因（ESR2）多态性与中国女性中风风险的关系，进一步评估ESR2和组合口服避孕药（COC）对卒中风险的基因 - 环境相互作用。

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来源
《Archives of medical research》 |2017年第2期|共9页
作者
Xu Zhenlin; Li Ying; Huang Xiaoping; Shen Wei; Bai Jianling; Shen Chong; Zhao Yang;
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作者单位

Nanjing Med Univ Sch Publ Hlth Dept Epidemiol &

Biostat 277 Feng Huang Xi Jie Nanjing 210036;

Nanjing Med Univ Sch Publ Hlth Dept Epidemiol &

Biostat 277 Feng Huang Xi Jie Nanjing 210036;

Nanjing Med Univ Sch Publ Hlth Dept Epidemiol &

Biostat 277 Feng Huang Xi Jie Nanjing 210036;

Nanjing Med Univ Sch Publ Hlth Dept Epidemiol &

Biostat 277 Feng Huang Xi Jie Nanjing 210036;

Nanjing Med Univ Sch Publ Hlth Dept Epidemiol &

Biostat 277 Feng Huang Xi Jie Nanjing 210036;

Nanjing Med Univ Sch Publ Hlth Dept Epidemiol &

Biostat 277 Feng Huang Xi Jie Nanjing 210036;

Nanjing Med Univ Sch Publ Hlth Dept Epidemiol &

Biostat 277 Feng Huang Xi Jie Nanjing 210036;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Estrogen receptor beta gene; Stroke; Oral contraceptives; Single nucleotide polymorphism;

机译：雌激素受体β基因;中风;口腔避孕药;单核苷酸多态性;

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专利

1. ESR2 Genetic Variants and Combined Oral Contraceptive Use Associated with the Risk of Stroke [J] . Xu Zhenlin, Li Ying, Huang Xiaoping, Archives of medical research . 2017,第2期

机译：ESR2遗传变异和组合口服避孕药与中风风险相关
2. Increased risk of stroke in oral contraceptive users carried replicated genetic variants: a population-based case–control study in China [J] . Chun Wang, Ying Li, Huiqiao Li, Human Genetics . 2012,第8期

机译：口服避孕药使用重复基因变异的中风风险增加：中国一项基于人群的病例对照研究
3. Estrogen receptor beta genetic variants and combined oral contraceptive use as relates to the risk of hypertension in Chinese women. [J] . Chen C, Li Y, Chen F, Archives of medical research . 2010,第8期

机译：雌激素受体β基因变异和联合口服避孕药的使用与中国女性患高血压的风险有关。
4. Oral contraceptives as a risk factor for developing breast cancer in women in the state of Alagoas: Case control study [C] . Araújo M. M. V., Rodrigues M. M. G., Rodrigues W. G.1 da Fonseca C. M., World Congress on Public Health . 2013

机译：口服避孕药作为妇女在Alagoas妇女中发育乳腺癌的危险因素：案例控制研究
5. Progesterone-only oral contraceptive pill, breast cancer, heart disease, and stroke. [D] . Samson, Marsha Ema. 2016

机译：仅黄体酮口服避孕药，乳腺癌，心脏病和中风。
6. Combined oral contraceptives: the risk of myocardial infarction and ischemic stroke [O] . Rachel E.J. Roach, Frans M Helmerhorst, Willem M. Lijfering, -1

机译：联合口服避孕药：心肌梗塞和缺血性中风的风险
7. Combined oral contraceptives: the risk of myocardial infarction and ischemic stroke [O] . Rachel E.J. Roach, Frans M Helmerhorst, Willem M. Lijfering, 2014

机译：组合口服避孕药：心肌梗死和缺血性卒中的风险
8. Oral Contraceptives and Breast Cancer. Summary Table of Studies of Breast CancerRisk Related to Oral Contraceptive Use (December 11, 1989) [R] . Malone, K. E. 1991

机译：口服避孕药和乳腺癌。与口服避孕药有关的乳腺癌风险研究总结表（1989年12月11日）

ESR2 Genetic Variants and Combined Oral Contraceptive Use Associated with the Risk of Stroke

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