Abutilon pannosum Abutilon pannosum stem bark enhances the aphrodisiac activities and spermatogenesis in rat

摘要

Abstract Abutilon pannosum (Forst.f.) Schlecht. is used for male sexual performance. In this study, we have investigated aphrodisiac potential of A.?pannosum stem bark methanol extract (APM) in rat. Male rats were administered with APM (400?mg/kg) on daily basis for 5, 10 and 15?days. Time interval for mount latency, intromission latency and post‐ejaculatory interval was decreased ( p ??.05) while time of ejaculatory latency, mount frequency, intromission frequency and ejaculatory frequency after 15?days were ( p ??.05) enhanced as compared to control rats. APM also increased ( p ??.05) penile erection index, copulatory rate and mount bout against control rats. Total count of spermatozoa was nonsignificantly increased whereas per cent of live spermatozoa and motile spermatozoa were increased ( p ??.05) in APM treated group after 10 and 15?days. Weight of testes, seminal vesicle, prostate and epididymis, and level of testosterone in serum increased ( p ??.05) after 10 and 15?days of APM administration to rat. Qualitative characterisation of APM indicated existence of alkaloids, terpenoids, coumarins, cardiac glycosides, phenols, flavonoids, saponins, tannins and sterols. Results of this study indicated aphrodisiac potential of A.?pannosum in rat and may be used to enhance sexual performance in human.