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Risky Alcohol Consumption and Associated Health Behaviour Among HIV-Positive and HIV-Negative Patients in a UK Sexual Health and HIV Clinic: A Cross-Sectional Questionnaire Study

机译:英国性健康和艾滋病毒诊所中HIV阳性和HIV阴性阴性患者的风险酒精消费和相关健康行为:横断面调查问卷研究

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摘要

Alcohol misuse has been associated with negative consequences among HIV-positive patients. Data on real prevalence of risky alcohol consumption among the HIV-positive population in the UK are lacking. A cross-sectional questionnaire study using standardised validated instruments among HIV-positive (n = 227) and HIV-negative (n = 69) patients was performed. The prevalence of risky alcohol consumption (AUDIT) and associations with depressive symptoms (PHQ-9), problematic drug use (DUDIT), adherence to ART (CASE Adherence Index), sexual behaviour and demographic characteristics were assessed among both patient groups independently. A quarter (25.1%) of HIV-positive patients and 36.1% of HIV-negative patients reported risky alcohol consumption (AUDIT-score >= 8). In the multivariable analysis among HIV-positive patients depressive symptoms (p = 0.03) and problematic drug use (p = 0.007) were associated with risky alcohol consumption. Among HIV-negative patients these associations were not present. Risky alcohol consumption among HIV-positive patients is prevalent, and together with depressive symptoms and problematic drug use, may influence HIV-disease progression and patients' wellbeing.
机译:酒精滥用与艾滋病毒阳性患者之间的负面后果有关。缺乏英国艾滋病毒阳性人群风险酒精消费的真正患病率的数据。进行了使用标准化验证仪器在HIV阳性(N = 227)和HIV阴性(n = 69)患者中的横截面调查问卷研究。在两个患者组织独立地,评估了风险症状(PHQ-9),有问题的药物使用(Dudit),遵守艺术(案例依从指数),性行为和人口统计特征的患病饮酒(审计)和关联的患病率。艾滋病毒阳性患者的四分之一(25.1%)和36.1%的HIV阴性患者报告风险饮酒(审计分数> = 8)。在艾滋病毒阳性患者中的多变量分析中,抑郁症状(P = 0.03)和有问题的药物使用(P = 0.007)与风险饮酒有关。在HIV阴性患者中,这些关联不存在。艾滋病毒阳性患者的风险酒精消耗普遍,并与抑郁症状和有问题的药物使用一起,可能影响艾滋病毒疾病进展和患者的幸福。

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