Prognostic Effect of CD20 Expression in Adult B-cell Acute Lymphoblastic Leukemia

摘要

Expression of CD20 in adult B- cell acute lymphoblastic leukemia has been associated with a poor prognosis. Previous studies have suggested treatment with rituximab can significantly improve event- free, although not overall, survival. The results from the present study of Hispanic ALL-B patients support the role of CD20 as a determinant of a poor prognosis and suggest that treatment with rituximab offers significant benefit.