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首页> 外文期刊>Current pharmacogenomics and personalized medicine >A Prospective Observational Pilot Study of Adverse Drug Reactions in Patients Admitted in the Geriatric Ward of a Tertiary Hospital in North India
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A Prospective Observational Pilot Study of Adverse Drug Reactions in Patients Admitted in the Geriatric Ward of a Tertiary Hospital in North India

机译:北印度高等院医院老年医院患者不良药物反应的前瞻性观察试验研究

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Background: Adverse Drug Reactions (ADRs) form one of the leading causes of morbidity and mortality particularly in the elderly population. Alterations in pharmacokinetics and pharmacodynamics with ageing results in increased ADRs which may be novel in respect to the young and may also vary from one older individual to another. These may hence be invaluable in personalized medicine. Objective: The primary objective of this pilot study was to find the occurrence of ADRs in north Indian elderly patients admitted in the Geriatric ward, to analyze its epidemiological attributes and to draw conclusions regarding its implications in designing individualized treatment regimens and plan for larger multi-centric studies.
机译:背景:不良药物反应(ADRS)形成一个特别是在老年人口中的发病率和死亡的主要原因之一。 药代动力学和药效学具有老化的改变导致增加的ADR,这可能是对年轻人的新颖,并且也可能与一个老年人不同于另一个人。 因此,这些可能在个性化药物中非常宝贵。 目的:该试点研究的主要目标是发现北印度老年患者ADRS的发生,以分析其流行病学属性,并在设计个性化治疗方案和规划方面的巨大意义上得出结论 以中心的研究。

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