The Synthetic and Anion-binding Ability of Novel Colorimetric Chemosensors Based on Azobenzol Derivatives: Experimental and Theoretical

摘要

Background: Azobenzol derivatives are important organic materials and show unique optical function.As a potential host, azobenzene has been broadly exploited in many areas because of its efficient inclusionability and easy derivatization by functional groups.Objective: A series of twelve novel compounds have been synthesized and optimized based on azobenzol derivatives.Method: The binding properties were evaluated for biologically important anions (F-, Cl-, Br-, I-, AcO- andH2PO4-) by theoretical investigation, UV-vis, fluorescence experiments.Results: The compound containing three nitro groups displayed the strongest binding ability for AcO- ionamong synthesized compounds. Theoretical investigation analysis revealed that the intramolecular hydrogenbond existed in the structure of the synthesized compounds.Conclusion: we have developed twelve compounds based on azobenzol derivatives. Compound 6 involvingthree nitro groups showed high sensitive and selective binding ability for acetate ion through multiple hydrogenbonds among anions tested including AcO-, F-, H2PO4-, Cl-, Br- and I- due to the conformational complementarityand higher basicity. Compound 6 also can be used as a colorimetric sensor for detecting acetate ion inenvironmental and pharmacy samples. The above results can provide a clue for the constructing of anion receptorbased on azobenzol derivatives.