TGF beta 1 Genetic Variants Predict Clinical Outcomes of HPV-Positive Oropharyngeal Cancer Patients after Definitive Radiotherapy

Tao Ye; Sturgis Erich M.; Huang Zhigang; Wang Ying; Wei Peng; Wang Jennifer Rui; Wei Qingyi; Li Guojun

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TGF beta 1 Genetic Variants Predict Clinical Outcomes of HPV-Positive Oropharyngeal Cancer Patients after Definitive Radiotherapy

机译：TGFβ1遗传变异预测明确放疗后HPV阳性口咽癌症患者的临床结果

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Purpose: TGF beta 1 plays a critical role in inflammation and immune responses and treatment response and survival. TGF beta 1 variants may affect its expression level or functional efficiency, thus modifying tumor status and survival in human papillomavirus (HPV)-positive squamous cell carcinoma of the oropharynx (SCCOP).

机译：目的：TGFβ1在炎症和免疫应答和治疗反应和存活中起着关键作用。 TGFβ1变体可能会影响其表达水平或功能效率，从而改变人乳头瘤病毒（HPV）肌瘤（HPV）的肿瘤状态和生存率的胃痛子（SCCOP）。

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《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2018年第9期|共9页
作者
Tao Ye; Sturgis Erich M.; Huang Zhigang; Wang Ying; Wei Peng; Wang Jennifer Rui; Wei Qingyi; Li Guojun;
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作者单位

Capital Med Univ Key Lab Otolaryngol Head &

Neck Surg Dept Otolaryngol Head &

Neck Surg Beijing;

Univ Texas MD Anderson Canc Ctr Dept Head &

Neck Surg Houston TX 77030 USA;

Capital Med Univ Key Lab Otolaryngol Head &

Neck Surg Dept Otolaryngol Head &

Neck Surg Beijing;

Univ Texas MD Anderson Canc Ctr Dept Bioinformat &

Computat Biol Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Biostat Houston TX 77030 USA;

Univ Texas MD Anderson Canc Ctr Dept Head &

Neck Surg Houston TX 77030 USA;

Duke Univ Med Ctr Duke Canc Inst Durham NC USA;

Univ Texas MD Anderson Canc Ctr Dept Head &

Neck Surg Houston TX 77030 USA;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
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专利

1. TGF beta 1 Genetic Variants Predict Clinical Outcomes of HPV-Positive Oropharyngeal Cancer Patients after Definitive Radiotherapy [J] . Tao Ye, Sturgis Erich M., Huang Zhigang, Clinical cancer research: an official journal of the American Association for Cancer Research . 2018,第9期

机译：TGFβ1遗传变异预测明确放疗后HPV阳性口咽癌症患者的临床结果
2. Potentially functional variants of p14ARF are associated with HPV-positive oropharyngeal cancer patients and survival after definitive chemoradiotherapy [J] . SongX., SturgisE.M., HuangZ., Carcinogenesis . 2014,第1期

机译：p14ARF的潜在功能性变体与HPV阳性口咽癌患者和明确放化疗后的存活率有关
3. Nomograms incorporating genetic variants in BMP/Smad4/Hamp pathway to predict disease outcomes after definitive radiotherapy for non‐small cell lung cancer [J] . Ju Yang, Ting Xu, Daniel R. Gomez, Cancer Medicine . 2018,第6期

机译：线型图结合BMP / Smad4 / Hamp途径中的遗传变异来预测非小细胞肺癌明确放疗后的疾病结局
4. Collaborative Clustering Of Subjects And Radiomic Features For Predicting Clinical Outcomes Of Rectal Cancer Patients [C] . Hangfan Liu, Hongming Li, Pamela Boimel, IEEE International Symposium on Biomedical Imaging . 2019

机译：主题和放射学特征的协作聚类预测直肠癌患者的临床结果
5. National and Institutional Outcomes Data in Head and Neck Cancers, and Functional and Patient Reported Outcomes in Patients with Oropharyngeal Cancers. [D] . Kansal, Ankit. 2017

机译：头颈癌的国家和机构结局数据，以及口咽癌患者的功能和患者报告结局。
6. TGF-β1 genetic variants predict clinical outcomes of HPV-positive oropharyngeal cancer patients after definitive radiotherapy [O] . Ye Tao, Erich M. Sturgis, Zhigang Huang, -1

机译：TGF-β1基因变异预测最终放疗后HPV阳性口咽癌患者的临床结局
7. Lymphocyte telomere length predicts clinical outcomes of HPV-positive oropharyngeal cancer patients after definitive radiotherapy [O] . Xiaoning Luo, Erich M Sturgis, Zheng Yang, 2019

机译：淋巴细胞端粒长度预测明确放疗后HPV阳性口咽癌患者的临床结果

TGF beta 1 Genetic Variants Predict Clinical Outcomes of HPV-Positive Oropharyngeal Cancer Patients after Definitive Radiotherapy

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