Mean platelet volume as a marker of thrombosis in patients with missed abortion

摘要

Early pregnancy loss is a common pregnancy complication with an incidence ranging between 50 and 70% of all conceptions [1]. The exact cause of it is still unknown. Mean platelet volume (MPV), an accurate measure of platelet size, is considered a marker and determinant of platelet function. Larger platelets with higher MPV values are hemostatically more reactive and produce higher amounts of the prothrom-botic factor thromboxane A_2, increasing the propensity to thrombosis [2, 3]. In the case of a missed abortion, there may be a liability for thrombosis whether an abnormality in the embryo is present or not.