Is mean platelet volume a predictive marker in patients with venous thrombosis?

摘要

I read with great interest 2 articles about the relationship between mean platelet volume (MPV) and venous thrombosis published online in your journal. Venous and arterial thromboses have been considered as distinct physiopathological concepts through thrombus formation. Arterial thrombi are found in areas of high shear stress and consist mostly of platelets and fibrin. Venous thrombi usually develop in low flow vessels and consist predominantly of erythrocytes and fibrin. Although the data suggest the MPV may potentially be useful as a predictive marker, there are a number of concerns related to the technological limitations and variations in the measuremeant methods of the MPV that need to be considered. Mean platelet volume does not report a routine part of the complete blood count because of the EDTA induced changes over time.