A sensitive quantitative assay for the determination of propafenone and two metabolites, 5‐hydroxypropafenone and N‐depropylpropafenone, in human K2EDTA plasma using LC–MS/MS with ESI operated in positive mode

Patel Harilal; Ghoghari Ashok; Bhatt Chandrakant; Shah Shaival; Jha Anilkumar; Desai Nirmal; Srinivas Nuggehally R.

首页> 外文期刊>Biomedical Chromatography: An International Journal Devoted to Research in Chromatographic Methodologies and Their Applications in the Biosciences >A sensitive quantitative assay for the determination of propafenone and two metabolites, 5‐hydroxypropafenone and N‐depropylpropafenone, in human K2EDTA plasma using LC–MS/MS with ESI operated in positive mode

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A sensitive quantitative assay for the determination of propafenone and two metabolites, 5‐hydroxypropafenone and N‐depropylpropafenone, in human K2EDTA plasma using LC–MS/MS with ESI operated in positive mode

机译：用于使用LC-MS / MS在人K2EDTA等离子体中测定丙酮酮和两种代谢物，5-羟基丙酮和正脱甲酰丙二酮的敏感定量测定，使用LC-MS / MS以正模式运行的ESI

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《Biomedical Chromatography: An International Journal Devoted to Research in Chromatographic Methodologies and Their Applications in the Biosciences》 |2019年第12期|共1页
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Patel Harilal; Ghoghari Ashok; Bhatt Chandrakant; Shah Shaival; Jha Anilkumar; Desai Nirmal; Srinivas Nuggehally R.;
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正文语种 eng
中图分类化学;
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1. A sensitive quantitative assay for the determination of propafenone and two metabolites, 5‐hydroxypropafenone and N‐depropylpropafenone, in human K2EDTA plasma using LC–MS/MS with ESI operated in positive mode [J] . Patel Harilal, Ghoghari Ashok, Bhatt Chandrakant, Biomedical Chromatography: An International Journal Devoted to Research in Chromatographic Methodologies and Their Applications in the Biosciences . 2019,第12期

机译：用于使用LC-MS / MS在人K2EDTA等离子体中测定丙酮酮和两种代谢物，5-羟基丙酮和正脱甲酰丙二酮的敏感定量测定，使用LC-MS / MS以正模式运行的ESI
2. A Sensitive and Rapid LC-MS-MS Method for Simultaneous Determination of Propafenone and Its Active Metabolite 5-Hydroxypropafenone in Human Plasma and Its Application in a Pharmacokinetic Study [J] . Chi Zhiyan, Liu Ruijuan, Li Ya, Journal of Chromatographic Science . 2017,第9期

机译：一种敏感和快速的LC-MS-MS-MS方法，用于同时测定人血浆中丙酮酮及其活性代谢物5-羟基丙酮及其在药代动力学研究中的应用
3. A rapid and sensitive LCa??MS/MS assay for the determination of propafenoneand its active metabolite 5a??hydroxy propafenone in human plasma usinghybrid SPE precipitation technology [J] . Palavan C.1, Seshagiri Rao J. V. L. N.2, Sujan Kumar D. P.1 Der Pharmacia Lettre . 2015,第4期

机译：混合固相萃取技术快速，灵敏地测定人血浆中普罗帕酮及其活性代谢物5a ??羟基普罗帕酮的LCa ?? MS / MS分析
4. Simultaneous Determination of udenafil and its Active Metabolite, DA-8164, in Free Fraction Human Plasma by LC-ESI/MS/MS [C] . Hwa Suk Kim, Seul Oh, Jun-Hwa Shim, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：通过LC-ESI / MS / MS同时测定udenafil及其活性代谢物，DA-8164，自由级分子血浆
5. The application of LC/ESI-MS/MS in the characterization of flavonoids in fruits and their disposition in humans [D] . Hong, Yun-Jeong 2006

机译：LC / ESI-MS / MS在表征水果中类黄酮及其在人体中的分布中的应用
6. An improved LC-MS/MS method for quantitative determination of ilaprazole and its metabolites in human plasma and its application to a pharmacokinetic study [O] . Gan Zhou, Zhi-rong Tan, Wei Zhang, 2009

机译：改进的LC-MS / MS方法定量测定人血浆中艾拉拉唑及其代谢物的方法及其在药代动力学研究中的应用
7. A Sensitive and Rapid LC–MS-MS Method for Simultaneous Determination of Propafenone and Its Active Metabolite 5-Hydroxypropafenone in Human Plasma and Its Application in a Pharmacokinetic Study [O] . Zhiyan Chi, Ruijuan Liu, Y Li, 2017

机译：一种敏感和快速的LC-MS-MS方法，用于同时测定人血浆中丙酮酮及其活性代谢物5-羟基丙酮及其在药代动力学研究中的应用
8. Novel Method for the Determination of Sildenafil (Viagra) and Its Metabolite (UK-103,320) in Postmortem Specimens Using LC/MS/MS and LC/MS/MS/MS [R] . Lewis, R. J., Johnson, R. D., Blank, C. L. 2000

机译：使用LC / ms / ms和LC / ms / ms / ms测定死后标本中西地那非（伟哥）及其代谢物（UK-103,320）的新方法

A sensitive quantitative assay for the determination of propafenone and two metabolites, 5‐hydroxypropafenone and N‐depropylpropafenone, in human K2EDTA plasma using LC–MS/MS with ESI operated in positive mode

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