A-36 CLINICAL SIGNIFICANCE OF MICROMETASTASIS DETECTED BY IMMUNOFLUORESCENCE ON TOUCH IMPRINTS OF SENTINEL LYMPH NODES IN PATIENTS WITH BREAST CARCINOMA

摘要

To compare the relative sensitivity of a new, lower cost manual liquid-based thin-layer preparation to conventional Pap smears using the cervical biopsy as the standard for comparison. MATERIALS AND METHODS: Patients were selected based on Pap smears previously screened as positive by conventional cytology or suspect for cervical cancer in the city of Barueri. Results from GluCyte liquid-based preparations, another conventional Pap smear, and biopsies were compared in this study. Patients had col-poscopic examination, and a new sample from the uterine cervix was obtained using the Rovers Cervex Brush. A new conventional smear was made, and the brush widi residual material was sent to the laboratory in the Synermed Preservative Vial. The Pap test samples were processed utilizing the GluCyte method, and both samples (conventional and liquid based) were stained using the conventional Pap staining method. When the biopsy was performed, it was sent at the same time to the laboratory and processed in the routine manner. The liquid-based and conventional smears were identified and randomly mixed, blinded and read by 3 expert cytologists. The results of conventional and liquid-based cytology smears were compared to evaluate the diagnostic agreement between the cytology preparations and the biopsies.