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Surgery of rheumatic mitral stenosis: comparison of different techniques.

机译:风湿性二尖瓣狭窄手术:不同技术的比较。

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OBJECTIVE: The breakthrough of percutaneous transvenous mitral commissurotomy (PTMC) has dramatically changed the indications for the surgical treatment of rheumatic mitral stenosis over the last decade. No recent studies comparing long-term results of PTMC, open mitral commissurotomy (OMC) and mitral valve replacement (MVR) with bileaflet prostheses are available in medical literature. METHODS AND RESULTS: Between January 1991 and December 1997, 313 patients with pure and isolated rheumatic stenosis were treated in our department. One hundred and eleven patients underwent PTMC, 82 OMC and 120 MVR.There was no statistical difference (p>0.05) between the mortality rates of the three groups of patients. No cases of hospital mortality were observed in the patients who underwent PTMC and OMC, whereas two patients (1.6%) died within 30 days after MVR. Seven year actuarial survival results are: 95.41+/-2(SE)% (PTMC), 98.05+/-1% (OMC) and 92.82+/-33% (MVR) (p=NS). Freedom from embolism was 98.78+/-1% in PTMC, 98.78+/-1% in OMC and 92.52+/-2% in MVR (p>0.05); freedom from reoperation was 88.43+/-8% in PTMC, 96.35%+/-2% in OMC and 97.72+/-1% in MVR (p>0.05).The mean NYHA class at the end of follow-up was lower in OMC (1.14+/-0.3) versus PTMC (1.39+/-0.6) and MVR (1.41+/-0.71) (p=0.001). CONCLUSIONS: Even though conservative techniques are the first option to consider in treating mitral valve stenosis, valve replacement with bileaflet prostheses no longer represents a limiting factor to survival and quality of life.
机译:目的:经皮二尖瓣二尖瓣合缝术(PTMC)的突破极大地改变了过去十年来风湿性二尖瓣狭窄的外科治疗适应症。在医学文献中,尚无关于将PTMC,二尖瓣开放性切开术(OMC)和二尖瓣置换术(MVR)与双叶假体的长期结果进行比较的近期研究。方法与结果:1991年1月至1997年12月,我科收治313例单纯性和单纯性风湿性狭窄患者。 11例患者接受了PTMC,82 OMC和120 MVR。三组患者的死亡率之间无统计学差异(p> 0.05)。在接受PTMC和OMC的患者中未观察到医院死亡病例,而在MVR后30天内有2例患者(1.6%)死亡。七年精算生存期结果是:95.41 +/- 2(SE)%(PTMC),98.05 +/- 1%(OMC)和92.82 +/- 33%(MVR)(p = NS)。 PTMC中无栓塞的发生率为98.78 +/- 1%,OMC中为98.78 +/- 1%,MVR为92.52 +/- 2%(p> 0.05); PTMC的再手术自由度为88.43 +/- 8%,OMC的为96.35%+ /-2%,MVR的为97.72 +/- 1%(p> 0.05)。随访结束时的平均NYHA等级较低OMC(1.14 +/- 0.3)与PTMC(1.39 +/- 0.6)和MVR(1.41 +/- 0.71)的差异(p = 0.001)。结论:尽管保守技术是治疗二尖瓣狭窄的首选方法,但双叶假体置换瓣膜已不再是生存和生活质量的限制因素。

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