Crizotinib effects on creatinine and non-creatinine-based measures of glomerular filtration rate.

摘要

If crizotinib-associated changes in creatinine-based kidney function suggest a change in dosing with either crizotinib or concomitant medications that are renally excreted, use of a non-creatinine-based assessment of kidney function, such as iothalamate assessments, should be considered before making a final decision.