Effect of blood flow occlusion on corticospinal excitability during sustained low-intensity isometric elbow flexion.

摘要

1 ) contractile failure with BFO, 2 ) a time-matched trial without restriction [free flow (FFiso)], and 3 ) contractile failure with free flow (FFfail). Time to failure for BFO (and FFiso) were ~80% shorter than that for FFfail ( P P P P > 0.05). The increase in normalized CMEP area was greater for BFO and FFfail compared with FFiso and for BFO compared with FFfail. MEP/CMEP area was not different among the protocols ( P > 0.05) and increased ~64% with time ( P NEW & NOTEWORTHY We have observed how blood flow occlusion modulates motor cortical, spinal, and peripheral excitability during and immediately after a sustained low-intensity isometric elbow flexion contraction to failure. We conclude that blood flow occlusion causes a greater and more rapid increase in motoneuronal excitability.